Search results: Sage Journals

Retricted accessReview articleFirst published December, 2024

Capivasertib: A Novel AKT Inhibitor Approved for Hormone-Receptor-Positive,HER-2-Negative Metastatic Breast Cancer

Alexa J. Luboff, David L. DeRemer

Annals of Pharmacotherapy

Free accessResearch articleFirst published January, 2019

Augmentation of Ouabain-Induced Increase in Heart Muscle Contractility by Akt Inhibitor MK-2206

Nahum Buzaglo, Mordechai Golomb, Haim Rosen [...]

Journal of Cardiovascular Pharmacology and Therapeutics

Free accessResearch articleFirst published October, 2006

Identification of Small-Molecule Inhibitors of Protein Kinase B (PKB/AKT) in an AlphaScreen™ High-Throughput Screen

Samantha Burns, Jonathan Travers, Ian Collins [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published October 27, 2020

Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway

Natália Chermont dos Santos Moreira, Jéssica Ellen Barbosa de Freitas Lima, Talita Perez Cantuaria Chierrito [...]

Journal of Alzheimer’s Disease

Free accessResearch articleFirst published February, 2005

Identification of Akt Pathway Inhibitors Using Redistribution Screening on the FLIPR and the IN Cell 3000 Analyzer

Betina Kerstin Lundholt, Viggo Linde, Frosty Loechel [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published April, 2020

MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling

Dankai Zhan, Xinxin Zhang, Jiahui Li [...]

Cancer Biotherapy and Radiopharmaceuticals

Open accessResearch articleFirst published 2025

Molecular Docking Appraisal of Pleurotus ostreatus Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment

Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi [...]

Bioinformatics and Biology Insights

Free accessResearch articleFirst published June, 2004

Development of a Fluorescence Polarization Bead-Based Coupled Assay to Target Different Activity/Conformation States of a Protein Kinase

Zhuomei Lu, Zhizhang Yin, Linda James [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published November, 2014

Rho GDP Dissociation Inhibitor Beta Promotes Cell Proliferation and Invasion by Modulating the AKT Pathway in Hepatocellular Carcinoma

Yang Fang, Jiang Yi, Lv Lizhi [...]

DNA and Cell Biology

Available accessResearch articleFirst published September, 2012

Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells

Mary Nashed, Jeffrey W Chisholm, R Ariel Igal

Experimental Biology and Medicine

Retricted accessReview articleFirst published December, 2024

Capivasertib: A Novel AKT Inhibitor Approved for Hormone-Receptor-Positive,HER-2-Negative Metastatic Breast Cancer

Alexa J. Luboff, David L. DeRemer

Annals of Pharmacotherapy

Free accessResearch articleFirst published January, 2019

Augmentation of Ouabain-Induced Increase in Heart Muscle Contractility by Akt Inhibitor MK-2206

Nahum Buzaglo, Mordechai Golomb, Haim Rosen [...]

Journal of Cardiovascular Pharmacology and Therapeutics

Free accessResearch articleFirst published October, 2006

Identification of Small-Molecule Inhibitors of Protein Kinase B (PKB/AKT) in an AlphaScreen™ High-Throughput Screen

Samantha Burns, Jonathan Travers, Ian Collins [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published October 27, 2020

Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway

Natália Chermont dos Santos Moreira, Jéssica Ellen Barbosa de Freitas Lima, Talita Perez Cantuaria Chierrito [...]

Journal of Alzheimer’s Disease

Free accessResearch articleFirst published February, 2005

Identification of Akt Pathway Inhibitors Using Redistribution Screening on the FLIPR and the IN Cell 3000 Analyzer

Betina Kerstin Lundholt, Viggo Linde, Frosty Loechel [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published April, 2020

MTH1 Inhibitor TH287 Suppresses Gastric Cancer Development Through the Regulation of PI3K/AKT Signaling

Dankai Zhan, Xinxin Zhang, Jiahui Li [...]

Cancer Biotherapy and Radiopharmaceuticals

Open accessResearch articleFirst published 2025

Molecular Docking Appraisal of Pleurotus ostreatus Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment

Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi [...]

Bioinformatics and Biology Insights

Free accessResearch articleFirst published June, 2004

Development of a Fluorescence Polarization Bead-Based Coupled Assay to Target Different Activity/Conformation States of a Protein Kinase

Zhuomei Lu, Zhizhang Yin, Linda James [...]

Journal of Biomolecular Screening

Available accessResearch articleFirst published November, 2014

Rho GDP Dissociation Inhibitor Beta Promotes Cell Proliferation and Invasion by Modulating the AKT Pathway in Hepatocellular Carcinoma

Yang Fang, Jiang Yi, Lv Lizhi [...]

DNA and Cell Biology

Available accessResearch articleFirst published September, 2012

Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells

Mary Nashed, Jeffrey W Chisholm, R Ariel Igal

Experimental Biology and Medicine