Short-Term Tumor Control and Acute Toxicity after Stereotactic Radiosurgery for Glomus Jugulare Tumors

Abstract

OBJECTIVE: Glomus jugulare tumors (GJT) have traditionally been treated by surgery or fractionated external beam radiation therapy (XRT). This study evaluates acute toxicity and short-term efficacy of single-fraction stereotactic radiosurgery (SRS) for the treatment of GJT.

STUDY DESIGN AND SETTING: Eight patients (age range 28-74) with GJT underwent SRS (Brainlab linear accelerator) as primary treatment. A nominal dose of 15-16 Gy was prescribed. RESULTS: After undergoing SRS, 7 of 8 patients (87.5%) reported complete resolution of presenting symptoms. Follow-up MRIs showed tumor stabilization in 100% of patients. Transient vertigo occurred in one patient. One patient suffered acute GI upset and transient lower cranial neuropathy.

CONCLUSION: Stereotactic radiosurgery is an effective alternative for patients with GJT in achieving tumor control and resolution of symptoms.

EBM rating: C-4

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