Abstract
A pig breeder presented with lichenification and dermatitis at light-exposed areas and noticed that his skin symptoms became worse after working in his piglet sty and during sunny weather. By extensive photopatch testing, sensitizations to olaquindox, choline chloride, quinosol, and chlorpromazine were revealed. Olaquindox and choline chloride are widely used pig feed additives in so-called medicated feed. Thus far, four cases of olaquindox-induced photocontact dermatitis have been reported. It seems to be associated with reduced minimal erythema doses and prolonged sensitivity to UVA and UVB. Because olaquindox is widely used in pig breeding, it should be considered if cases of photocontact dermatitis are encountered in farmers. Olaquindox, chlorpromazine, and choline chloride share chemical structures of alkylamines or hydroxy-substituted alkylamines. Because a contact dermatitis to choline chloride has not been reported, it might be a cross-reaction to chlorpromazine or olaquindox.
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