There is evidence that the human contrast-sensitivity function (CSF) is mediated by the spatiotemporal characteristics of magno and parvo neurons early in the visual pathway. In this study we use a measure of contrast gain derived from simple reaction times, to investigate the neural substrates of suprathreshold performance. The results reveal the activity of two mechanisms having distinctly different contrast-gain characteristics. Comparing these to neurophysiological data, we find that the magnocellular system dominates close-to-threshold detection and probably forms the basis of the achromatic CSF, whereas the parvocellular system dominates detection at higher contrasts, when the magnocellular system saturates.
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References
1.
AtchisonD AScottD H, 2002“Monochromatic aberrations of human eyes in the horizontal visual field”Journal of the Optical Society of America A192180–2184
2.
BauerUScholzMLevittJObermayerKLundJ, 1999“A model for the depth-dependence of receptive field size and contrast sensitivity of cells in layer 4C of macaque striate cortex”Vision Research39613–629
3.
CronerL JKaplanE, 1995“Receptive fields of P and M ganglion cells across the primate retina”Vision Research357–24
4.
DerringtonMLennieP, 1984“Spatial and temporal contrast sensitivity of neurones in lateral geniculate nucleus of macaque”Journal of Physiology357219–240
GoodchildA KGhoshK KMartinP R, 1996“Comparison of photoreceptor spatial density and ganglion cell morphology in the retina of human, macaque monkey cat, and the marmoset Callithrix jacchus”Journal of Comparative Neurology36655–75
7.
HarwerthRLeviD, 1978“Reaction time as a measure of suprathreshold grating detection”Vision Research181579–1586
8.
HicksTLeeBVidyasagarT, 1983“The responses of cells in macaque lateral geniculate nucleus to sinusoidal gratings”Journal of Physiology337183–200
9.
KaplanEBenardeteE, 2001“The dynamics of primate retinal ganglion cells”Progress in Brain Research13417–34
10.
KaplanELeeBShapleyR, 1990“New views of primate retinal function”, in Progress in Retinal Research Eds OsborneE NChaderG (Oxford: Pergamon Press) pp 273–336
11.
KaplanEShapleyR, 1986“The primate retina contains two types of ganglion cells, with high and low contrast sensitivity”Proceedings of the National Academy of Sciences of the USA832755–2757
12.
KulikowskiJ, 1989“The role of P and M systems: (c) psychophysical aspects”, in Seeing Contour and Colour Eds KulikowskiJDickinsonCMurrayI (Oxford: Pergamon Press) pp 232–237
13.
LeeB, 1996“Receptive field structure in the primate retina”Vision Research36631–644
14.
LeeB B, 2004“Paths to colour in the retina”Clinical and Experimental Optometry87239–248
15.
LeeBMartinPValbergA, 1989“Sensitivity of macaque retinal ganglion cells to chromatic and luminance flicker”Journal of Physiology414223–243
16.
LeeBPokornyJSmithVMartinPValbergA, 1990“Luminance chromatic modulation sensitivity of macaque ganglion cells and human observers”Journal of the Optical Society of America A72223–2237
17.
LenniePD'ZmuraM, 1988“Mechanisms of color vision”Critical Review of Neurobiology3333–400
18.
LenniePPokornyJSmithV C, 1993“Luminance”Journal of the Optical Society of America A101283–1293
19.
LivingstoneMHubelD, 1988“Segregation of form, color, movement, and depth: anatomy, physiology, and perception”Science240740–749
20.
LundJWuQHadinghamPLevittJ, 1995“Cells and circuits contributing to functional properties in area V1 of macaque monkey cerebral cortex: Bases for neuroanatomically realistic models”Journal of Anatomy187563–581
21.
McKeefryD JParryN R AMurrayI J, 2003“Simple reaction times in color space: The influence of chromaticity, contrast, and cone opponency”Investigative Ophthalmology & Visual Science442267–2276
22.
MeriganWMaunsellJ, 1993“How parallel are the primate visual pathways?”Annual Review of Neuroscience16369–402
23.
MullenK TKingdomF A, 2002“Differential distributions of red-green and blue-yellow cone opponency across the visual field”Visual Neuroscience19109–118
24.
MurrayI JPlainisS, 2003“Contrast coding and magno/parvo segregation revealed in reaction time studies”Vision Research432707–2719
25.
NavarroRMorenoEDorronsoroC, 1998“Monochromatic aberrations and point-spread functions of the human eye across the visual field”Journal of the Optical Society of America A152522–2529
26.
ParryN, 2001“Contrast dependency of reaction times to chromatic gratings”Color Research and Application26S161-S164
27.
PerryVOehlerRCoweyA, 1984“Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey”Neuroscience121110–1123
28.
PlainisSMurrayI J, 2000“Neurophysiological interpretation of human visual reaction times: effect of contrast, spatial frequency and luminance”Neuropsychologia381555–1564
29.
RodieckRBinmoellerKDineenJ, 1985“Parasol and midget ganglion cells of the human retina”Journal of Comparative Neurology233115–132
30.
RovamoJVirsuVNasanenR, 1978“Cortical magnification factor predicts the photopic contrast sensitivity of peripheral vision”Nature27154–56
31.
SclarGMaunsellJLennieP, 1990“Coding of image contrast in central visual pathways of the macaque monkey”Vision Research301–100
32.
ShapleyRHawkenM, 1999“Parallel retino-cortical channels and luminance”, in Color Vision: From Genes to Perception Eds GegenfurtnerKSharpeL (Cambridge: Cambridge University Press) pp 221–234
33.
VidyasagarT RKulikowskiJ JLipnickiD MDreherB, 2002“Convergence of parvocellular and magnocellular information channels in the primary visual cortex of the macaque”European Journal of Neuroscience16945–956
34.
WieselTHubelD, 1966“Spatial and chromatic interactions in the lateral geniculate body of the rhesus monkey”Journal of Neurophysiology291115–1156
35.
YehTLeeBKremersJ, 1995“Temporal response of ganglion cells of the macaque retina to cone-specific modulation”Journal of the Optical Society of America A12456–464
