Abstract
Cellular Reprogramming is the only peer-reviewed journal dedicated to cellular reprogramming mechanisms, technologies and applications. Cellular reprogramming is a diverse and growing discipline that studies the reversal or modification of cellular identity. The field aims to understand how cell fate is acquired, maintained and inherited in homeostatic conditions and what happens when cell identity is hijacked in disease. Due to the vast therapeutic potential of cellular reprogramming, efforts have also been placed to harness cell fate engineering for clinical applications. The journal covers but is not limited to the different ways cellular reprogramming can be achieved experimentally, including nuclear transfer, cell fusion or expression of defined factors.
Under the editorial leadership of Filipe Pereira, PhD, Associate Professor, Faculty of Medicine, Lund University, Cellular Reprogramming is currently seeking manuscripts for a special issue with a dedicated focus on Direct Cell Reprogramming. Original research papers and reviews are welcome.
Deadline for manuscript submission: September 31, 2021
*Please include “Direct Cell Reprogramming” in your cover letter when submitting your manuscript.
Direct cell reprogramming, also called transdifferentiation, allows the reprogramming of one somatic cell type directly into another, without transiting through pluripotency. The pace of research in direct cell reprogramming has been tremendous leading to the de novo generation of macrophages, dendritic cells, neurons, hepatocytes, cardiomyocytes, adipocytes and many other cell-types. The identification of the master transcription factor combinations imposing cell fate by direct reprogramming also supports guided lineage differentiation strategies from stem cells. In addition to transcription factors, direct cell reprogramming can also be elicited in vitro or in vivo with miRNAs, epigenetic modulators or with chemical compounds.
Direct cell reprogramming and transdifferentiation
Reprogramming mediated by defined factors and underlying biology
Inducing direct cell reprogramming with miRNAs, epigenetic modulators or small molecules
In vivo lineage reprogramming
Molecular mechanism of cell identity including epigenetics and epitranscriptomics
Cell and gene therapy based on direct cell reprogramming paradigms
Disease modelling and drug screening utilizing direct cell reprogramming
Rapid, high-quality peer review and editorial attention
Exposure to thousands of thought-leaders in your field, maximizing readers, citations, and downloads
Fast Track online-ahead-of-print publication
Global availability in over 170 countries
Open Access publication options
Competitive author benefits program
Questions or pre-submission queries? Authors may vet ideas directly with Guest Editors or the Editors via e-mail before submitting. Please refer to the Cellular Reprogramming website for instruction for authors and manuscript submission. We look forward to receiving your manuscripts and to your active participation in the Journal!