Abstract

The results of a genome-wide meta-analyis of genetic data from more than individuals has linked 102 genetic variants and 269 genes with depression, and found associations between the psychiatric disorder and a number of behavioral traits. The researchers, headed by a team at the University of Edinburgh, say their study results offer new insights into the genetic basis of depression, and could lead to new treatment approaches.
“These findings are further evidence that depression is partly down to our genetics,” commented lead investigator Andrew McIntosh, Ph.D., professor of biological psychiatry and a senior clinical research fellow at the University of Edinburgh Centre for Clinical Brain Sciences. The international team, including scientists in the U.K., Europe, the U.S., and Australia, reported the findings in Nature Neuroscience.
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