Abstract
The past few years have seen tremendous progress in the identification of new types and classes of CRISPR-Cas systems and exciting new properties of their associated effector functions. As the CRISPR toolbox continues to grow, so too do the myriad applications of CRISPR genome editing technology, from basic to translational and clinical research. It is also gratifying to see the adaptation of the diverse CRISPR-Cas systems to develop new methods for genome editing such as base editing and prime editing, as well as applications beyond editing such as epigenetic regulation and 3D genome control.
This special issue of New types of CRISPR-Cas systems and nucleases New methods using CRISPR for genomic control New applications using CRISPR for gene and cell therapy New approaches using CRISPR for synthetic biology and biomaterial engineering New software tools for monitoring and studying CRISPR New methods to predict and design guides and test efficiency and specificity CRISPR screens CRISPR diagnostics tools Using CRISPR to build model systems and organisms
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The CRISPR Journal is dedicated to publishing cutting-edge research and opinion on genome editing and CRISPR biology. It is a truly multidisciplinary journal, providing a high-profile platform to share and discuss advances in research and applications for the rapidly growing CRISPR/genome editing community.