Abstract: Background:
Botanicals are increasingly incorporated into skincare products. Although allergic contact dermatitis due to botanicals is recognized, data describing the prevalence of positive patch tests to botanicals are sparse.
Objective:
To report the Mayo Clinic experience of patch testing to selected botanical products in the standard, extended standard, fragrance, and plant series.
Methods:
IRB-approved retrospective study of the Mayo Clinic experience with patch testing to botanicals from 1997 to 2017.
Results:
In total, 12,169 people were patch tested to botanicals in the standard, extended standard, fragrance, and plant series; 4032 were men and 8137 were women. The mean age of the population tested was 54 (standard deviation 17.7) years. Almost 11% (1320/12,169) of the patch-tested population exhibited positive reactions to at least 1 botanical agent. Myroxylon pereirae resin 25% was the most common positive allergen in the series. Patients who had positive reactions to at least 1 botanical agent were more (19.8%) likely to have a positive reaction to at least 1 additional botanical than those patients who did not have any positive tests. Most patients presented with generalized involvement (334) or involvement of the hands (284) or face (232).
Conclusion:
Physicians should be aware of the high prevalence of allergic contact dermatitis and patch test positivity associated with botanical products.
Supplementary Material
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