T
his month's issue of DNA and Cell Biology features an article that highlights two of the journal's ongoing priorities—to present mechanistic studies of disease alongside clinical research and to showcase the work of young scientists. Sarojini and coworkers (including an undergraduate student) present their findings concerning the antiviral properties of tetherin in vesicular stomatitis virus infection of mouse neuronal cells in “Interferon-Induced Tetherin Restricts Vesicular Stomatitis Virus Release in Neurons.” Tetherin-knockdown cells were created and analyzed. Sarojini et al. found that tetherin expression is induced by interferon-β and interferon-γ, and tetherin greatly restricts release of progeny virus. These findings provide insight into the molecular mechanisms of the antiviral response in mammalian neuronal cells. DNA and Cell Biology is currently soliciting articles exploring molecular mechanisms of disease. For more information, please see the journal's Web site (www.liebertpub.com/dna) or contact the editorial office (dnaandcellbiology@yale.edu).
