Counting Genes: A Human Genome Conundrum

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References

Venter

, Adams

, Myers

, et al. The sequence of the human genome. Science, 2001; 291(5507):1304–1351; doi: 10.1126/science.1058040

Lander

, Linton

, Birren

, et al. Initial sequencing and analysis of the human genome. Nature, 2001; 409(6822):860–921; doi: 10.1038/35057062

Salzberg

. Open questions: How many genes do we have?. BMC Biol, 2018; 16(1):94; doi: 10.1186/s12915-018-0564-x

Nurk

, Koren

, Rhie

, et al. The complete sequence of a human genome. Science, 2022; 376(6588):44–53; doi: 10.1126/science.abj6987

Kuijjer

, Tung

, Yuan

, et al. Estimating sample-specific regulatory networks. iScience, 2019; 14:226–240; doi: 10.1016/j.isci.2019.03.021

Glass

, Huttenhower

, Quackenbush

, et al. Passing messages between biological networks to refine predicted interactions. PLoS One, 2013; 8(5):e64832; doi: 10.1371/journal.pone.0064832

Weighill

, Ben Guebila

, Glass

, et al. Predicting genotype-specific gene regulatory networks. Genome Res, 2022; 32(3):524–533; doi: 10.1101/gr.275107.120

Glinos

, Garborcauskas

, Hoffman

, et al. Transcriptome variation in human tissues revealed by long-read sequencing. Nature, 2022; 608(7922):353–359; doi: 10.1038/s41586-022-05035-y