Comparative Study of the Changes in Partial Pressure of Plasma Carbon Dioxide During Carbon Dioxide Insufflation into the Intraperitoneal and Preperitoneal Spaces

Abstract

Background:

We aimed to compare plasma concentrations of carbon dioxide (CO₂) in dogs that underwent intra- and preperitoneal CO₂ insufflation.

Materials and Methods:

Thirty dogs were studied. Ten formed a control group, 10 underwent intraperitoneal CO₂ insufflation, and 10 underwent preperitoneal CO₂ insufflation. General anesthesia with controlled ventilation was standardized for all dogs. After stabilizing the anesthesia, blood samples were collected at predetermined times and were sent for immediate gasometric analysis. Analysis of variance was used for comparing variables.

Results:

The plasma CO₂ concentration in the intraperitoneal insufflation group increased significantly more than in the preperitoneal insufflation group and was significantly greater than in the control group (P < 0.05). The pH values in the intraperitoneal group were lower than in the preperitoneal group (P < 0.05).

Conclusion:

The data from this study suggest that a greater plasma concentration of CO₂ is achieved by insufflation at constant pressure into the intraperitoneal space than into the preperitoneal space.