Program of the Thirtieth Annual Meeting of the Surgical Infection Society

1. MAINTENANCE OF THE GUT EPITHELIAL BARRIER VIA VAGAL NERVE STIMULATION PROTECTS AGAINST SECONDARY PULMONARY INJURY AFTER THERMAL INJURY

Michael J. Krzyzaniak, MD, Carrie Y. Peterson, MD, William H. Loomis, BS, James G Putnam, BS, Vince Kennedy, Vishal Bansal, MD, Brian Eliceri, PhD, Andrew N. Baird PhD, Raul Coimbra MD, PhD - University of California, San Diego

 Discussant: Basil A. Pruitt Jr., MD

2. DELAY OF ELECTIVE SURGERY FOR HIGH VOLUME PROCEDURES: THE IMPACT ON INFECTIOUS COMPLICATIONS

Todd R. Vogel, MD, MPH, Viktor Y. Dombrovskiy MD, MPH, PhD, Stephen F. Lowry, MD, MBA - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School

 Discussant: E. Patchen Dellinger, MD

3. THE ROLE OF DENDRITIC CELLS IN ENTEROBACTER SAKAZAKII-INDUCED DISRUPTION OF THE EPITHELIAL CELL BARRIER: IMPLICATIONS FOR THE PATHOGENESIS OF NEC

Claudia N. Emami, MD, Rahul Mittal, PhD, Prasdarao V. Nemani, PhD, Henri R. Ford, MD, MHA - Children's Hospital Los Angeles, University of Southern California

 Discussant: William G. Cioffi, MD

4. URINARY TRACT INFECTIONS SIGNIFICANTLY WORSEN OUTCOMES IN TRAUMA PATIENTS; AN ANALYSIS OF 8,841 PATIENTS

Sean F. Monaghan, MD, Daithi S. Heffernan, MD, Rajan K Thakkar, MD, Steven E. Reinert, Jason T. Machan, PhD, Shea Gregg, MD, Matthew S. Kozloff, MD, Michael D. Connolly, MD, Charles A. Adams, MD, William G Cioffi, MD - Brown University, Rhode Island Hospital

 Discussant: John C. Marshall, MD

5. TLR4 INDUCED AUTOPHAGY INCREASES BACTERIAL INTERNALIZATION BY ENTEROCYTES

Matthew D. Neal, MD, Chhinder P. Sodhi, PhD, Ward M. Richardson MD, Amin Afrazi, BS, Richard Siggers, PhD, David J. Hackam, MD, PhD - Division of Pediatric Surgery, Department of Surgery, University of Pittsburgh Medical Center

 Discussant: Henri R. Ford, MD

6. PROPHYLACTIC ANTIBIOTIC DAYS AS A PREDICTOR OF SENSITIVITY PATTERNS IN ACINETOBACTER PNEUMONIA

Parth B. Amin, MD, Louis J. Magnotti, MD, Peter E. Fischer, MD, Martin A. Croce, MD, Timothy C. Fabian, MD - Presley Trauma Center, University of Tennessee, Memphis

 Discussant: Lena M. Napolitano MD

7. EVIDENCE THAT LETHAL GUT- DERIVED SEPSIS DUE TO CANDIDA ALBICANS IN MICE IS DEPENDENT ON THE LOCAL CONCENTRATION OF PHOSPHATE

Kathleen S. Romanowski, MD, Alex Zaborin, PhD, Vesta Valuckaite, MD, Trissa A. Babrowski, MD, David Fink, MD, Irina Morozova, MS, Donald C Liu, MD, PhD, Jeffery B. Matthews, MD, Olga Zaborina PhD, John C. Alverdy, MD - University of Chicago

 Discussant: Pamela A. Lipsett, MD

8. THE PRESENCE OF SPECIFIC BACTERIAL ORGANISMS PREDICTS MORTALITY IN PATIENTS WITH INTRA-ABDOMINAL INFECTIONS

William H. Leukhardt, MD, Jeffrey W. Carter, MD, Manjunath Haridas, MD, Tazo S. Inui, MD, Mark A. Malangoni, MD, Jeffrey A. Claridge, MD, MS - MetroHealth Medical Center

 Discussant: Roger W. Yurt, MD

9. VAGAL NERVE STIMULATION MODULES INTESTINAL TIGHT JUNCTION PROTEIN EXPRESSION THROUGH THE ACTIVATION OF ENTERIC GLIA CELLS

Todd W. Costantini, MD, Carrie Y. Peterson, MD, James G. Putnam, BS, William H. Loomis, BS, Seok Yong Ryu, MD, PhD, Vishal Bansal, MD, Raul Coimbra, MD, PhD - University of California, San Diego

 Discussant: John C. Alverdy, MD

10. INTESTINAL PHOSPHATE DEPLETION DEVELOPS DURING HUMAN CRITICAL ILLNESS AND ACTIVATES THE VIRULENCE OF KEY COLONIZING PATHOGENS ASSOCIATED WITH GUT-DERIVED SEPSIS

Alexander V. Zaborin, PhD, Kathleen Romanowski, MD, Irina Morozova, MS, Cindy Bethel, MT, (ASCP), Trissa Babrowski, MD, Andrea Olivas, MD, David Fink, MD, Karen Frank, MD, PhD, Donald Liu MD, PhD, Olga Zaborina, PhD, John C. Alverdy, MD - University of Chicago

 Discussant: Jared Huston, MD

11. TIR DOMAIN VARIANTS OF MAL/TIRAP RESULT IN ALTERED TLR4 SIGNALING

Kaysie L. Banton, MD, Karen A. McCulloch, BS, Karen R. Wasiluk, PhD - University of Minnesota

 Discussant: Edwin A. Deitch, MD

12. LATE POST-TRAUMATIC IMMUNE DYSFUNCTION: THE ROLE OF TLR2 AND TLR4 SIGNALING

Sophie S Darwiche, MD, Xiangcai Ruan, MD, Melanie Scott, MD, PhD, Rosemary Hoffman, PhD, Hans-Christoph Pape, MD, Timothy R. Billiar, MD - University of Pittsburgh

 Discussant: Saman Arbabi, MD

13. MKP-1 PROMOTES TOLERANCE TO TLR LIGANDS IN ENTEROCYTES

Jin Wang, MS, Anatoly V. Grishin, PhD, Henri R. Ford, MD, MHA - Children's Hospital Los Angeles

 Discussant: Marc Jeschke, MD

14. PLATELET CD154 MEDIATES REMOTE TISSUE INJURY FOLLOWING MESENTERIC ISCHEMIA AND REPERFUSION

Peter H. Lapchak, MSc, PhD, Poonam Rani, MSc, Lakshmi Kannan, PhD, Jurandir J. Dalle Lucca, MD, George C. Tsokos, MD -Beth Israel Deaconess Medical Center and Harvard Medical School

 Discussant: Stephen F. Lowry, MD, MBA

15. BETA BLOCKADE PREVENTS HEMATOPOIETIC PROGENITOR CELL SUPPRESSION FOLLOWING HEMORRHAGIC SHOCK

Ihab O. Elhassan, MD, Edward J. Hannoush, MD, Walter D. Alzate, BSc, MSc, Ziad C. Sifri, MD, David H. Livingston, MD, Alicia M. Mohr, MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School

 Discussant: Alfred Ayala, PhD

16. P-GLYCOPROTEIN IS REQUIRED FOR BREAST MILK-INDUCED PROTECTION FROM NECROTIZING ENTEROCOLITIS IN A NEONATAL MOUSE MODEL

Shannon L. Castle, MD, Jin Wang, MS, Monica Williams, BS, Anatoly V. Grishin, PhD, Jeffrey S. Upperman, MD*, Henri R. Ford, MD, MHA - Childrens' 'Hospital Los Angeles, University of Southern California

 Discussant: Evan P. Nadler, MD

17. A CONCISE INSTRUMENT FOR SEPSIS SCREENING IN GENERAL SURGERY PATIENTS

Laura J. Moore, MD, Stephen L. Jones, MD, Krista L. Turner, MD, Samual R. Todd, MD, Shirley Kung, RN, Frank Stokes RN, ACNP, Craig W. Johnson, PhD, Gloria L. Beriones, RN, Frederick A. Moore, MD - The Methodist Hospital, Houston

 Discussant: Samir Fahkry, MD

18. ROUTE OF FEEDING DIFFERENTIALLY INFLUENCES MONOCYTE GENE EXPRESSION

Beth-Ann Shanker, MD, Chun Choi, MD, Susette M.Coyle, RN, MSN, Marie A. Macor, RN, John L. Nosher, MD, Steve E. Calvano, PhD, Stephen F. Lowry, MD - University of Medicine and Dentistry of New Jersey -Robert Wood Johnson Medical School

 Discussant: Martin A. Croce, MD

19. PREDICTIVE VALUE OF IL-8 FOR SEPSIS AND SEVERE INFECTIONS AFTER BURN INJURY-A CLINICAL INVESTIGATION.

Robert Kraft, MD, David N. Herndon, MD, Juquan Song, MD, Gabriela A. Kulp, MS, Marc G. Jeschke, MD, PhD - University of Texas Medical Branch, Galveston

 Discussant: Henri R. Ford, MD, MPA

20. INTERVAL APPENDECTOMY AFTER NON-OPERATIVE MANAGEMENT OF ACUTE APPENDICITIS AT A CANCER CENTER

Tiffany T. Fancher, MD, Frederic M. Pieracci, MD, MPH, Soumitra Eachempati, MD, Laila Rashidi, MS, Garrett M Nash, MD, MPH - Memorial Sloan Kettering Hospital, New York

 Discussant: Matthew Rosengart, MD, MPH

21. MASSIVE TRANSFUSION DOES NOT CAUSE INFECTIONS IN THE CRITICALLY ILL

William D. Dutton, MD, Chadi T. Abouassaly, MD, Bryan A. Cotton, MD, MPH, Addison K. May, MD, Oliver L. Gunter, MD - Vanderbilt University Medical Center

 Discussant: Philip S. Barie, MD, MBA

22. CHRONOLOGICAL STUDY OF BACTERIAL FLORA IN CONTAMINATED WOUNDS

Shirin Towfigh, MD, Tatyan Clarke, MD, Ankur Gupta, MD, Diane M. Citron, MS - Cedars-Sinai Medical Center

 Discussant: Kamal M. F. Itani, MD

23. CEFAZOLIN DOSING FOR SURGICAL PROPHYLAXIS IN MORBIDLY OBESE PATIENTS

Vanessa P. Ho, MD, David P. Nicolau, PharmD, Gregory F. Dakin, MD, Alfons Pomp, MD, Barrie S. Rich, MD, Christopher W. Towe, MD, Philip S. Barie, MD, MBA - Weill Cornell Medical College

 Discussant: J. Wesley Alexander, MD

24. URETERAL STENT PLACEMENT IS A SIGNIFICANT RISK FACTOR FOR THE DEVELOPMENT OF BK VIREMIA AFTER RENAL TRANSPLANTATION

Leon Kushnir, MD, Karinn Chambers, MD, Michael H. Gallichio, MD, David J. Conti, MD - Albany Medical College of Union University

 Discussant: Robert G. Sawyer, MD

25. PARENTERAL NUTRITION (PN) IMPAIRS LYMPHOTOXIN RECEPTOR (LTbR) SIGNALING VIA NF-kB

Jinggang Lan, PhD, Aaron F. Heneghan, PhD, Yoshifumi Sano, MD, Mark Jonker, MD, Jiro Omata, MD, Yang-Xin Fu, MD, PhD, Wentong Xu, MD, Joe Pierre, MA, Kenneth Kudsk, MD - University of Wiscinsin-Madison

 Discussant: Paul Bankey, MD PhD

26. VARIABLE IGA PROTEASE ACTIVITY BY BACTERIAL PATHOGENS: EFFECT ON PMN INFLAMMATORY POTENTIAL

Lawrence N. Diebel, MD, David M. Liberati, MS - Wayne State University

 Discussant: Ori D. Rotstein, MD

27. TREATMENT EFFECTS OF RECOMBINANT HUMAN SOLUBLE THROMBOMODULIN IN PATIENTS WITH SEVERE SEPSIS: PRELIMINARY HISTORICAL CONTROL STUDY

Kazuma Yamakawa, MD, Tomoyoshi Mohri, MD, Takeyuki Kiguchi, MD, Junichi Kitayama, MD, Hiroki Matsuda, MD, Yasushi Nakamori, MD, Satoshi Fujimi, MD. Sponsor: William Cheadle, MD- Osaka General Medical Center

 Discussant: Michael A. West, MD, PhD

28. ILEAL FATTY ACID BINDING PROTEIN (I-FABP) A NOVEL BIOMARKER FOR ACUTE INTESTINAL ISCHEMIA AND RESULTANT LUNG INJURY

Rachel G. Khadaroo, MD, PhD, Spyridon Fortis, MD, Cathy Streutker, MD, MSc, Haibo Zhang, MD, PhD - University of Alberta

 Discussant: Mark A. Wilson, MD, PhD

29. HUMAN MILK INDUCES DOSE- AND TIME- DEPENDENT P-GLYCOPROTEIN EXPRESSION IN HUMAN ENTEROCYTE CELL LINES

Ashanti L. Franklin, BA, Yigit Guner, MD, Monica Williams, BS, Jeffrey S. Upperman, MD, Anatoly Grishin, PhD, Henri R. Ford, MD, MHA - Children's Hospital Los Angeles, University of Southern California

 Discussant: Timothy R. Billiar, MD

30. IMMUNE-RELATED BIOMARKERS AND THE DEVELOPMENT OF NOSOCOMIAL INFECTION IN ICU PATIENTS

Chun W. Choi, MD, Beth-Ann Shanker, MD, MS, Susette M. Coyle, RN, Marie A. Macor, RN, Steve E. Calvano, PhD, Stephen F. Lowry, MD - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School

 Discussant: James A. Lederer, PhD

31. PEROXYNITRITE MEDIATES VASCULAR LEAKAGE VIA PROMOTING ANGIOPOEITIN-2 IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS-INDUCED SEPSIS

Perenlei Enkhbaatar, MD, PhD, Yong Zhu, MD, PhD, Sebastian Rehberg, MD, Yusuke Yamamoto, MD, PhD, Linda Sousse, BS, Lillian D. Traber, RN, David Herndon, MD, Daniel L. Traber, PhD - University of Texas Medical Branch, Galveston

 Discussant: Philip Efron, MD

32. THE INTERFERON REGULATORY FACTOR-1 REGULATES THE BALANCE BETWEEN APOPTOSIS AND AUTOPHAGY IN ENDOTOXEMIA

Lemeng Zhang, Pinhua Pan, John Evankovich, Jon Cardinal, Timothy Billiar, MD, Allan Tsung, MD - University of Pittsburgh Medical Center

 Discussant: Jared Huston, MD

33. REPORT CARD ON SURGICAL CARE IMPROVEMENT PROJECT (SCIP): NNIS INFECTION DATA 2001 THROUGH 2006

John Mihran Davis, MD, Yen-Hong Kuo, ScM, MS, Yen-Liang Kuo, MD, Nasim Ahmed, MD - Jersey Shore University Medical Center

 Discussant: Donald E. Fry, MD

34. RECONSIDERATION FOR CULTURING VASCULAR CATHETERS FOR SUSPECTED CR-BSI IN THE ICU

Alexander Rose, MD, Jing Zhao, PharmD, Krista Wahby, PharmD, Bryan Dotson, PharmD, Steven Tennenberg, MD - Wayne State University School of Medicine

 Discussant: Lewis Kaplan, MD

35. THE NORMALIZATION OF HYPERCORTISOLEMIA POST-BURN WITH KETOCONAZOLE DOES NOT ATTENUATE THE HYPERMETABOLIC CATABOLIC RESPONSE

Felicia N. Williams, MD, David N. Herndon, MD, David L. Chinkes PhD, Gabriela A. Kulp, MS, Arny Ferrando, PhD, Oscar E. Suman, PhD, Celeste Finnerty, PhD, Robert Kraft, MD, Ludwik K. Branski, MD, Ahmed M. Al-mousawi, MD, Mark G. Jeschke, MD, PhD - University of Texas Medical Branch-Galveston

 Discussant: Lillian Kao, MD

36. EFFECT OF BODY MASS INDEX (BMI) ON CLINICAL RESPONSE TO TREATMENT FOR COMPLICATED INTRAABDOMINAL INFECTION (cIAI)

Nicholas Namias, MD, Darcy A. Hille, MS - University of Miami Miller School of Medicine

 Discussant: Vincente H. Gracias, MD

37. WITHDRAWN

38. FAILURE TO NORMALIZE LYMPHOCYTE REDUCTION FOLLOWING TRAUMA IS ASSOCIATED WITH INCREASED MORTALITY, INDEPENDENT OF THE LEUKOCYTOSIS PATTERN

Daithi S. Heffernan, MD, Sean F. Monaghan, MD, Rajan K. Thakkar, MD, Jason T. Machan, PhD, Alfred Ayala, PhD, William G. Cioffi, MD - Department of Surgery, Rhode Island Hospital, Brown University

 Discussant: William Chien-Chen Chiu, MD

39. EMPIRIC ANTIBIOTICS PENDING BAL RESULTS IN PATIENTS WITHOUT PNEUMONIA SIGNIFICANTLY ALTERS THE FLORA BUT NOT THE RESISTANCE PROFILE IF A SUBSEQUENT PNEUMONIA DEVELOPS

Rajan K. Thakkar, MD, Sean F. Monaghan, MD, Daithi S. Heffernan, MD, Charles A. Adams, MD, Michael D. Connolly, MD, Shea Gregg, MD, Matthew S. Kozloff, MD, William G. Cioffi, MD- Department of Surgery, Rhode Island Hospital, Brown University

 Discussant: Philip S. Barie, MD, MBA

40. LOCAL VARIATIONS IN EPIDEMIOLOGY, MICROBIOLOGY, AND OUTCOME OF NECROTIZING SOFT TISSUE INFECTIONS: A MULTI-CENTER STUDY

Lillian S. Kao, MD, MPH, Debbie F. Lew, MPH, Samer N. Arab, MD, S. Rob Todd, MD, Matthew M. Carrick MD, Michael G. Corneille, MD, Samir S. Awad, MD, Kevin P. Lally, MD, MS - University of Texas Health Science Center at Houston

 Discussant: Jose Diaz, MD

P1. A MULTICENTER, RANDOMIZED, CONTROLLED CLINICAL TRIAL COMPARING CIPROFLOXACIN WITH MEROPENEM FOR TREATMENT OF POSTOPERATIVE INFECTIONS, FINAL REPORT OF POSTOPERATIVE INFECTION TREATMENT STUDY GROUP OF JAPAN SOCIETY FOR SURGICAL INFECTION

Shinya Kusachi, MD, PhD, Yoshiki Takahashi, MD, PhD, Koumei Kato, MD, PhD, Shigeto Oda, MD, PhD, Hiromitsu Takeyama, MD, PhD, Keiji Mashita MD, PhD, Shinichi Kobayashi, PhD, Yoshinobu Sumiyama MD, PhD- Japan Society of Surgical Infection

P2. ANTIBIOTIC REGIMEN AND TIMING OF PROPHYLAXIS ARE IMPORTANT FACTORS FOR LIMITING SURGICAL SITE INFECTION (SSI) IN ELECTIVE ABDOMINAL COLORECTAL SURGERY (ECRS)

Vanessa P. Ho, MD, Philip S. Barie, MD, MBA, Sharon L. Stein, MD, Koiana Trencheva, MS, Jeffrey W. Milsom, MD, Sang W. Lee, MD, Toyooki Sonoda, MD - Weill Cornell Medical College

P3. MEASURING SPATIAL DIFFERENCES IN PSEUDOMONAS AERUGINOSA DISTRIBUTION AND VIRULENCE ACTIVATION RELATED TO INTESTINAL ISCHEMIA REPERFUSION INJURY

David Fink, MD, Kathleen Romanowski, MD, Trissa Babrowski, MD, Vesta Valuckaite, MD, Alex Zaborin, PhD, Valeriy Poroyko, PhD, Irina Morozova, MS, Olga Zaborina, PhD, John Alverdy, MD - University of Chicago

P4. THE INFLUENCE OF INOS ON THE AUTOPHAGIC RESPONSE IN SEPSIS

Evie H. Carchman, MD, Brian S. Zuckerbraun, MD - University of Pittsburgh Medical Center

P5. IS THE MORBIDITY OF SECONDARY PERITONITIS A RESULT OF THE PATHOGENS EXPRESSING ENHANCED VIRULENCE

Trissa A. Babrowski, MD, Kathleen Romanowski, MD, David Fink, MD, Donald Liu, MD, PhD, Olga Zaborina, PhD, John Alverdy, MD - University of Chicago

P6. PROTEIN KINASE C PLAYS A ROLE IN ENTEROBACTER SAKAZAKII INDUCED INTESTINAL EPITHELIUM PERMEABILITY

Quin Y. Liu, MD, Rahul Mittal, PhD, Anatoly Grishin, PhD, Henri R. Ford, MD, Nemani V. Prasadarao, PhD - Children's Hospital Los Angeles

P7. COMPARISON OF ANTIMICROBIAL SUSCEPTIBILITY AND INCIDENCE OF EXTENDED-SPECTRUM BETA-LACTAMASE-PRODUCING ISOLATES IN MEDICAL INTENSIVE CARE UNITS VERSUS SURGICAL INTENSIVE CARE UNITS: RESULTS FROM SMART 2008–2009

Robert Badal, BS, Samuel Bouchillon, MD, Meredith Hackel, PhD, Aaron Johnson, BS - IHMA, Inc

P8. CEFTAROLINE ACTIVITY AGAINST CLINICAL ISOLATES OF STAPHYLOCOCCUS AUREUS, INCLUDING METHICILLIN-RESISTANT STRAINS (MRSA), FROM UNITED STATES (USA) HOSPITALS

Helio S. Sader, MD, PhD, Donald Biek, Ian Critchley, David J. Farrell, PhD, Ronald N. Jones, MD - JMI Laboratories

P9. PROPRANOLOL SUPPRESSES APOPTOSIS AND PRODUCTION OF INFLAMMATORY CYTOKINES IN LPS-STRESSED HUMAN MACROPHAGE-LIKE THP-1 CELLS

Kita Katsuhiro, PhD, Felicia Williams, MD, Rong Chu, Olga Obie, Gabreila Kulp, MS, David N. Herndon MD, Marc G. Jeschke, MD, PhD - University of Texas Medical Branch-Galveston

P10. DO BLOOD STREAM INFECTIONS AFFECT OUTCOME IN TRAUMA PATIENTS? Ziad C Sifri MD, Alicia A Mohr MD, Helen S. Horng, PharmD, Robert Lavery, MS, David H. Livingston, MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School

P11. QUANTITATIVE WOUND CULTURES - AN IMPORTANT MONITORING FACTOR IN CLINICAL PRACTICE

Robert Kraft, MD, Ahmed A Al-Mousawi, MD, David N. Herndon, MD, Song Juquan, MD, Marc G. Jeschke, MD, PhD - University of Texas Medical Branch, Galveston

P12. IMPACT OF TIMING OF TRACHEOSTOMY IN THE INCIDENCE OF PNEUMONIA FOLLOWING SEVERE HEAD INJURY

Nasim Ahmed, MD, Yen-Hong Kuo, ScM, MS, Yen-Liang Kuo, MD, John M. Davis, MD - Jersey Shore University Medical Center

P13. CAN WE FIND BETTER MARKERS FOR IMMUNE AND PHYSIOLOGICAL DYSFUNCTION IN THE CRITICALLY ILL? THE CASE FOR PD-1

Sean F. Monaghan, MD, Rajan K. Thakkar, MD, Mai L. Tran, BS, Xin Huang, PhD, William G. Cioffi, MD, Alfred Ayala, PhD, Daithi S. Heffernan, MD, - Rhode Island Hospital/Alpert Medical School of Brown University

P14. TEMPORARY ABDOMINAL CLOSURE IN PATIENTS WITH SEVERE INTRAABDOMINAL INFECTION: A COHORT STUDY

Elio Sanchez, MD, Oscar Heilbron, MD, Maria F. Jimenez, MD, Fabian Gil, MsC, Aura Rivera, MD, Nelson Nino MD, Juan Ayala, MD, Alvaro Sanchez, MD, MsC, Juan C. Puyana, MD - Pontificia Universidad Javeriana

P15. IS THERE A RELATIONSHIP BETWEEN ELEVATED VANCOMYCIN TROUGH CONCENTRATIONS (VT) AND INCREASED EFFICACY OR TOXICITY

Bruce H. Ackerman, PharmD, Kristen Phillips, Robert E. Guilday, MD, Mary L. Patton, MD, Linwood R. Haith Jr., MD - Crozer-Chester Medical Center

P16. PHYSIOLOGICAL LEUKOCYTOSIS IS NOT PHYSIOLOGIC FOLLOWING NON-TRAUMA SPLENECTOMY

Kathleen S. Romanowski, MD, Alaine Kamm, APN, Alex Bailey BS, Kevin K Roggin MD, Jeffery B Matthews MD, John C. Alverdy, MD - University of Chicago

P17. E-101 SOLUTION, A NOVEL ANTISEPTIC INTENDED FOR DIRECT APPLICATION WITHIN A SURGICAL WOUND TO PREVENT SURIGICAL SITE INFECTION: BLINDED, CONTROLLED PHASE 1 SKIN IRRITATION STUDY IN HEALTHY VOLUNTEERS

Peter O'Hanley PhD, MD, MPH, Christopher Beausoleil, CCRP, Kelly O'Hanley, MD, MPH, Steve Stephens - Exoxemis Inc.

P18. THE REDUCTION OF HEPATIC ALBUMIN EXPRESSION IS ASSOCIATED WITH ER STRESS DEACTIVATED EEF2 AFTER BURN INJURY

Juquan Song, MD, Robert Kraft MD, Xiaojun Zhang, MD, David N. Herndon, MD, Darren Boehning, PhD, Marc G. Jeschke, MD, PhD - Shriners Hospitals for Children and the University of Texas Medical Branch, Galveston

P19. INVOLVEMENT OF ENDOTOXIN IN THE MORTALITY OF MICE WITH GUT-DERIVED SEPSIS DUE TO METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

Masashi Uramatsu, Tetsuya Matsumoto, Kazuhiro Tateda, Shuichi Miyazaki, Tetsuya Horino, Masaski Tanabe, Kazutoshi Shibuya, Junko Sato, Shinya Kusachi, Keizo Yamaguchi - The Third Department of Surgery, Toho University Ohashi Hospital, Japan

P20. ANTIMICROBIAL ACTIVITY AND SPECTRUM OF THE NOVEL CEPHALOSPORIN CEFTAROLINE TESTED AGAINST BACTERIAL ISOLATES CAUSING SKIN AND SKIN STRUCTURE INFECTIONS IN USA MEDICAL CENTERS

David J. Farrell, PhD, Ian Critchley, Donald Biek, Ronald N. Jones MD, Helio S Sader MD, PhD - JMI Laboratories

P21. SEASONALITY OF PATHOGENS: A 7-YEAR STUDY OF CULTURE RESULTS FROM A SURGICAL ICU

Stefan Engstrom, Patrick R. Norris, Kenneth A. Debelak, Raymond L. Mernaugh, Sarah D. Valenti, Judith M. Jenkins, Michael B. Daly, Addison K. May, MD, Erik M. Boczko - Vanderbilt University

P22. ANTIBIOTICS PRIOR TO PEG PLACEMENT SIGNIFICANTLY REDUCES SURGICAL SITE INFECTIONS IN CRITICALLY INJURED TRAUMA PATIENTS

Ian R. Driscoll, MD, Gerard P. De Castro, MD, Grant V. Bochicchio, MD, MPH, Shijun Zhu, PhD, Sara M. Edeiken, Kelly Bochicchio, RN, MS, Obeid N. Ilahi, MD, Manjari Joshi, MD, Thomas M. Scalea, MD - Walter Reed Army Medical Center

P23. THE DEVELOPMENT OF RETROGRADE BACTERIAL EPIDIDYMITIS FOLLOWING VASECTOMY

Amani D. Politano, MD, Tony Mammen, MD, Raymond A. Costibile, MD, Jeffrey J. Lysiak, PhD, Terry T. Turner, PhD - University of Virginia (Sponsor: Robert G. Sawyer, MD)

P24. CONTEMPORARY PREDICTORS OF CONVERSION FROM LAPAROSCOPIC TO OPEN APPENDECTOMY

Patrick L. Wagner, MD, Soumitra R. Eachempati, MD, Lynn J. Hydo, RN, MBA, Frederic M. Pieracci, MD, MPH, Marie Bartholdi, Ben-Paul N. Umunna, Jian Shou, MD, Philip S. Barie, MD, MBA - NewYork-Presbyterian Hospital/Weill Cornell Medical Center

P25. ANTIBIOTIC USE AND SURGICAL MANAGEMENT IN 217 PATIENTS WITH MRSA SKIN AND SOFT TISSUE INFECTIONS

Peter K. Kim, MD, Dena G. Arumugam, BA, Stanley S. Cho, MPH, Stanislav Nosik, MD, Hugh Boothe, PhD - Jacobi Medical Center

P26. PREHOSPITAL INTUBATION FACTORS AND VENTILATOR ASSOCIATED PNEUMONIA IN TRAUMA PATIENTS

Heather L. Evans, MD, MS, Keir J. Warner, BS, Eileen M. Bulger, MD, Sam R. Sharar, MD, Ronald V. Maier, MD, Joseph Cuschieri, MD - Harborview Medical Center, University of Washington

P27. BLOOD TRANSFUSION INDUCES LATE CHANGES IN SPLEEN LEUKOCYTES

Philip A. Efron, MD, Dina C. Nacionales, MD, Kindra Kelly-Scumpia, PhD, Alex G. Cuenca, MD, Matthew Delano, MD, PhD, Darwin N. Ang, MD, PhD, MPH, Lyle L. Moldawer, PhD - University of Florida

P28. MECHANISTIC COMPUTATIONAL REPRESENTATION OF PATHOGEN RESPONSE TO MICROENVIRONMENT CHANGES DURING HOST STRESS

John Seal, MD, John Alverdy, MD, Trissa Babrowski, MD, David Fink, MD, Kathleen Romanowski, MD, Olga Zaborina, PhD, Gary An, MD - University of Chicago

P29. EVALUATION OF THE APACHE II, SOFA, SIRS, & ISS SCORING SYSTEMS IN PREDICTING OUTCOME IN CRITICALLY ILL TRAUMA PATIENTS

Gerard P. De Castro, MD, June Hsu, MPH, Grant V. Bochicchio, MD, MPH Kelly Bochicchio, RN, MS, Thomas M. Scalea, MD - University of Maryland School of Medicine

P30. COMBINATION THERAPY WITH CASPOFUNGIN AND VORICONAZOLE IN INVASIVE ASPERGILLOSIS IN SURGICAL PATIENTS

Christian Geltner, MD, Ingrid Stelzmueller, MD, Cornelia Lass-Floerl, MD, Hugo JR Bonatti MD - Pulmonology, Natters

P31. MOTOR VEHICLE BLUNT SPINAL CORD TRAUMA AND POSTTRAUMATIC INFECTION: WHO IS AT RISK

Douglas R. Fraser, MD, Viktor Y. Dombrovskiy, MD, PhD, MPH, Todd R. Vogel, MD, MPH - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson University Hospital, New Brunswick

P32. MACROPHAGE GENETIC REPROGRAMMING DURING CHRONIC PERITONITIS IS AUGMENTED BY LPS PRETREATMENT

Ziad Kanan, MD, James Peyton, MS, Sarah Gardner, BS, William G. Cheadle, MD - University of Lousville

P33. MAKING SOUND USE OF SCARCE DATA: EXAMINING THE IMPACT OF REPEAT POSITIVE CULTURES IN A DATASET OF MICROBIOLOGY FINDINGS

Stefan Engstrom, Patrick R. Norris, Kenneth A. Debelak, Raymond L. Mernaugh, Sarah D. Valenti, Judith M. Jenkins, Michael B. Daly, Addison K. May, MD, Erik M. Boczko - Vanderbilt University

P34. ACUTE APPENDICITIS- NOT JUST FOR THE YOUNG

Brian G. Harbrecht, MD, Jason W. Smith, MD, Glen A. Franklin, MD, J. David Richardson, MD - University of Louisville

P35. ALCOHOL ABUSE INCREASED POSTOPERATIVE INFECTION AND LENGTH OF HOSPITAL STAY ON ESOPHAGEAL CANCER RESECTIONS

Yen-Hong Kuo, ScM, MS, Nasim Ahmed, MD, Yen-Liang Kuo, MD, John M. Davis, MD - Jersey Shore University Medical Center

P36. ROLE OF RESISTANT GRAM-POSITIVE BACTERIA IN TREATMENT FAILURE FOR PERCUTANEOUS DRAINAGE OF POST-OPERATIVE COMPLICATED INTRA-ABDOMINAL INFECTION (CIAI)

Callisia N. Clarke, MD, Yun Miao, MD, PhD, Ross Ristagno, MD, Syed Ahmad, MD, Joseph Solomkin, MD - University of Cincinnati

P37. MUCORMYCOSIS IN A BURN ICU

Mark O. Hardin, MD, John D. Ritchie, MD, Josiah D. Freemyer, Christopher E. White, MD - U.S. Army Institute of Surgical Research (Sponsor: William G. Cheadle, MD)

P38. USING OF A DATA MINING FOR PREDICTION OF INFECTED PANCREATIC NECROSIS

Andrey A. Litvin, MD, PhD - Gomel Regional Clinical Hospital, Gomel State Medical University, Belarus

P39. IS ANGIOPOIETIN-2 ELEVATED IN TRAUMA PATIENTS WITH EXTRAPULMONARY ALI/ARDS?

Joanne Lomas-Neira, PhD, Rajan Thakkar, MD, Sean Monaghan, MD, Nicholas Carter BA, Alfred Ayala PhD, Daithi Heffernan, MD - Rhode Island Hospital, Alpert School of Medicine at Brown University

P40. INTRACOLONIC VANCOMYCIN FOR SEVERE CLOSTRIDIUM DIFFICILE COLITIS

Peter K. Kim, MD, Heesun C. Um, PharmD, Sal Ahmad, MD, Christina Coyle, MD, Sheldon Teperman, MD, Hugh Boothe, PhD, PharmD - Jacobi Medical Center

P41. MULTIDISCIPLINARY PERFORMANCE IMPROVEMENT (PI) TASK FORCE PROJECT MARKEDLY REDUCED AND ELIMINATED RESISTANT ACINETOBACTER BAUMANII/HAEMOLYTICUS (AB)

Cynthia L. Reigart BSN, Bruce H. Ackerman, PharmD, Meghan Stair-Buchman, BSN, Diane Herder, LPN, Pamela Adams, Christine Young, MBA, Robert E. Guilday, MD, Mary L. Patton, MD, Linwood R. Haith, Jr., MD, William D. Ravreby, MD - Crozer-Chester Medical Center

P42. OUTCOMES ASSOCIATED WITH PROLONGED INFUSIONS OF PIPERACILLIN/TAZOBACTAM IN CRITICALLY ILL PATIENTS

Daryl Schiller, PharmD, Fariborz Rezai, MD, Michael C. Meadows, MD, Edward H. Gray, DO, Kristin Fless, MD, Ronald S. Chamberlain MD, MPA, Paul C Yodice MD - Saint Barnabas Medical Center (Sponsor: William G. Cheadle, MD)

P43. ASSESSMENT OF THE TREATMENT OF ACINETOBACTER BAUMANNII FOLLOWING THE OUTBREAK OF A MULTI-RESISTANT CLONE AND A VARIANT CLONE IN A BURN TREATMENT CENTER

Bruce H. Ackerman, PharmD, Pamela Adams, Christine Young, MBA, Cynthia L. Reigart, BSN, Robert E. Guilday, MD, Mary L. Patton, MD, Linwood R. Haith, Jr., MD, William D. Ravreby MD - Crozer-Chester Medical Center

P44. CLOSTRIDIUM DIFFICILE INFECTION MAY REQUIRE SURGICAL MANAGEMENT IN CHILDREN

Jose M. Prince MD, Megan Sippey, BA, John D. Rutkoski, MD, Kevin P. Mollen, MD, Marian G. Michaels, MD, MPH, Brian S. Zuckerbraun, MD, Richard L. Simmons, MD, Barbara A. Gaines, MD - Children's Hospital of Pittsburgh

P45. CLINICAL IMPLICATIONS OF VIRUS-ASSOCIATED NEPHROPATHY AFTER RENAL TRANSPLANTATION

Helen P. Cathro, MD, Costi D. Sifri, MD, Douglas Keith, MD, Robert G. Sawyer, MD, Timothy L. Pruett MD, Kenneth Brayman, MD, PhD, Hugo JR. Bonatti, MD - Department of Pathology, University of Virginia

P46. COHORTING AND SUPERISOLATION IN A SINGLE INTENSIVE CARE UNIT IN AN EFFORT TO REDUCE PATIENT-TO-PATIENT TRANSMISSION

Laura H. Rosenberger, MD, Tjasa Hranjec, MD, MS, Rosemarie Metzger, MD, MPH, Brian R. Swenson, MD, MS, Robert G. Sawyer, MD - University of Virginia

P47. IMPACT OF TRAUMA CENTER LEVEL IN THE INCIDENCE OF PNEUMONIA FOLLOWING SEVERE HEAD INJURY

Nasim Ahmed, MD, Yen-Hong Kuo, ScM, MS, Yen-Liang Kuo, MD, John M. Davis. MD - Jersey Shore University Medical Center

P48. PROCALCITONIN IS A USEFUL MARKER TO DIFFERENTIATE BETWEEN INFECTION AND INFLAMMATION IN TRAUMA PATIENTS UNDERGOING ORTHOPEDIC PROCEDURES

Chadi T. Abouassaly, MD, Rondi Kauffman, MD, MPH, Heather Macnew, MD, Elizabeth O'Keefe, PhD, Alison Woodworth, PhD, Addison May, MD - Vanderbilt University Medical Center

P49. CRYPTOSPORIDIOSIS INCREASES TACROLIMUS LEVELS IN SOLID ORGAN RECIPIENTS: EXPERIENCE WITH SEVEN ADULT CASES FROM TWO CENTERS AND REVIEW OF THE LITERATURE

Hugo J.R. Bonatti, MD, Luis F. Barroso, MD, Robert G. Sawyer, MD, Kenneth Brayman, MD, Camielle N. Kotton, MD, Costi D. Sifri, MD - University of Virginia

P50. WITHDRAWN

P51. ACINETOBACTER BAUMANNI: A COLLATERAL DAMAGE PATHOGEN. A REVIEW OF RISK FACTORS AND CURRENT TREATMENT RECOMMENDATIONS

Kenji Kamanaka, BA, Michael C. Meadows, MD, Ronald S. Chamberlain MD, MPA - University of Medicine and Dentistry of New Jersey (Sponsor: William G. Cheadle, MD)

P52. SURGICAL SITE INFECTION IN LAPAROSCOPIC INGUINAL HERNIORRHAPY SURGICAL SITE INFECTION IN LAPAROSCOPIC INGUINAL HERNIORRHAPY

Maris S. Jones, MD, Charles R. St. Hill, MD, Shawn Tsuda, MD, Annabel E. Barber, MD - University of Nevada School of Medicine

P53. A MULTIDISCIPLINARY TEAM APPROACH TO REDUCING CLBSI IN THE ICU

Lynne W. Campbell, BSN, MSN, Jeanne Zack, PhD, Nancy Hansen, BSN, Linda Odnoha, BSN, Kevin Stuckert, MHA, Tracy Hathorn, RD, Susan Tuttle, PharmD, Marilyn Kole, MD, Jeffrey M. Scott, DO - Lee Memorial Health System

P54. SURGICAL INFECTION AND RISK FACTORS IN A GENERAL SURGERY SERVICE: A PROSPECTIVE STUDY

Pablo Vazquez Aragon, Pedro Cascales Sanchez, Maria Teresa Villar Canovas, Antonio Serafin Valero Linan, Juan Luis Rueda Martinez, Antonio Prat Calero, Maria Abad Martinez - General and University Hospital-Albacete, Spain

P55. SCEDIOSPORIUM BRAIN ABSCESSES IN A PATIENT WITH A PATENT FOREMEN OVALE CAUSED BY SINUSITIS AND FUNGAL PNEUMONIA FOLLOWING A WORK-RELATED BOILER EXPLOSION

Linwood R. Haith Jr. MD, Bruce H. Ackerman, PharmD, Heidi Hornbeek, MD, Mary L. Patton, MD, Robert E. Guilday, MD - Crozer-Chester Medical Center

P56. LIPOPOLYSACCHARIDE ALTERS THE GENETIC EXPRESSION OF KEY ENZYMES IN CERAMIDE METABOLISM

Mae F. Cantos, BSc, MD, Andras Kapus, MD, PhD, Menachem Ailenberg, PhD, Ori D Rotstein, MD - University of Toronto, St. Michael's Hospital

P57. A CASE OF CAT BITE INFECTION AS POLYMICROBIAL INFECTION CAUSED BY PASTEURELLA MULTOCIDA AND PREVOTELLA SPECIES

Yuka Yamagishi, MD, Hiroshige Mikamo, MD, PhD - Aichi Medical University

P58. NASAL SWAB SPECIMENS THAT ARE ROUTINELY COLLECTED TO SCREEN FOR MRSA IN INTENSIVE CARE UNITS CAN BE USED TO PREDICT THE PRESENCE OF MRSA IN CLINICAL CULTURES

Matthew C. Byrnes, MD, Titi Adegboyega, BA, Andrew Riggle, BA, Gregory Beilman, MD, Jeffrey Chipman, MD - University of Minnesota

P59. ABDOMINAL WALL WOUNDS SURROUNDING HIGH OUTPUT ENTEROCUTANEOUS FISTULAS CAN BE SUCCESSFULLY SKIN GRAFTED

Matthew Byrnes, MD, Andrew Riggle, BA, Greg Beilman, MD, Jeffrey Chipman MD - University of Minnesota

P60. CALCIFIC UREMIC ARTERIOLOPATHY-A COMBINED AGGRESSIVE CONJOINT NEPHROLOGY/BURN SURGERY MANAGEMENT

Linwood R. Haith, MD, Erica R. Podolsky, MD, Robert E. Guilday, MD, Mary Lou Patton, MD, Surekha Neeli, MD, Nathan Okechukwu, MD - Crozer Chester Medical Center

P61. TUMESCENT ANTIBIOTIC DELIVERY FOR SSI PROPHYLAXIS

Jeffrey A. Klein MD, MPH, Atoussa Cameron, RN, JoAnn Coker, RN, Loralie Langman, MD, Christine Snozek, MD - University of California, Riverside

P62. INCREASED INFECTIONS ARE ASSOCIATED WITH NON-OPERATIVE TRANSFUSIONS IN BURN PATIENTS

Joseph A. Posluszny Jr., MD, Chindo Hicks, PhD, Ravi Shankar, PhD, Richard L. Gamelli, MD - Loyola University Medical Center, Case Western Reserve University School of Medicine

P63. SINGLE CELL METAGENOMIC ANALYSIS OF GUT BACTERIA FROM HUMAN INFANTS WITH NECROTIZING ENTEROCOLITIS

Valeriy Poroyko, PhD, John Alverdy, MD, Donald Liu, MD, Michael Morowitz MD - University of Chicago

41. TRAFFICKING OF THE TLR4 INHIBITOR IRAK-M VIA NOD2 LIMITS TLR4 RESPONSIVENESS IN INTESTINAL EPITHELIAL CELLS

Matthew D. Neal, MD, Amin Afrazi, BS, Chhinder Sodhi, PhD, David J. Hackam, MD, PhD - Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center

 Discussant: David Greenhalgh, MD

42. SINGLE NUCLEOTIDE POLYMORPHISM A829G IN THE TRANSACTIVATION DOMAIN OF THE HUMAN GLUCOCORTICOID RECEPTOR PRODUCES HYPERACTIVITY

Kelly Tung, MD, MS, Tajia L. Green, BS, Sally T. Nguyen, BS, Debora Lim, BS, Kiho Cho, DVM, PhD, David G Greenhalgh, MD - Shriners Hospitals for Children Northern California/University of California, Davis Medical Center

 Discussant: Craig M. Coopersmith, MD

43. TERMINATION OF HAND HYGIENE SURVEILLANCE IS ASSOCIATED WITH INCREASED NOSOCOMIAL INFECTIONS IN THE SURGICAL INTENSIVE CARE UNIT

Dorothy W. Bird, MD, Dale Ford, RN, MPH, Carol Sulis, MD, Peter A. Burke, MD, Suresh Agarwal, MD - Boston University Medical Center

 Discussant: Sandra M. Swoboda, RN, MSN

44. ANTIBIOTIC TIME-LAG COMBINATION THERAPY WITH FOSFOMYCIN FOR PATIENTS WITH POSTOPERATIVE INTRA-ABDOMINAL ABSCESS

Shinya Kusachi, MD, PhD, Jiro Nagao, MD, PhD, Junko Sato, PhD, Tomoaki Saito, MD, Masashi Uramatsu, MD, Yoichi Nakamura, MD, PhD, Yoshihisa Saida, MD, PhD, Manabu Watanabe, MD, PhD, Yasushi Okamoto, MD, PhD, Koji Asai, MD, PhD, Toshiyuki Enomoto, MD, PhD, Ryohei Watanabe MD, Yoichi Arima, MD, PhD, Yuichi Yoshida, MD, PhD- Toho University Ohashi Hospital

 Discussant: Patrick O'Neill, MD

45. CHANGES IN LEUKOCYTE COUNT ARE MORE IMPORTANT IN PREDICTING INFECTION THAN ABSOLUTE LEUKOCYTE COUNT IN CRITICALLY ILL TRAUMA PATIENTS

Jeffrey W. Carter, MD, William H. Leukhardt, MD, Joseph F. Golob, MD, Adam M. Fadlalla, PhD, Jeffrey A. Claridge, MD, MS - MetroHealth Medical Center

 Discussant: Michael J. Morowitz, MD PhD

46. THE INFLAMMATORY RESPONSE IN COMBAT WOUNDS IS ASSOCIATED WITH CRITICAL COLONIZATION

Trevor S. Brown, PhD, Jason S. Hawksworth, MD, Forest R. Sheppard, MD, Douglas K. Tadaki, PhD, Eric A. Elster, MD - Naval Medical Research Center, Bethesda

 Discussant: Laura Moore, MD

47. DOES WITHHOLDING EARLY INTRAVENOUS FAT EMULSION FROM PARENTERAL NUTRITION REDUCE INFECTIONS DURING CRITICAL ILLNESS?

Anthony T. Gerlach, PharmD, Claire V. Murphy, PharmD, BCPS, Sheela Thomas, MS, RD, LD, Lydia Pourzanjani, RD, LD, Stan Stawicki, MD, Steven Steinberg, MD, Melissa Whitmill, MD, Charles H. Cook MD* - The Ohio State University

 Discussant: Kenneth Kudsk, MD

48. HYPOXIA-INDUCED UPREGULATION OF AUTOPHAGY IN MOUSE HEPATOCYTES IS DEPENDENT ON CASPASE-1

Qian Sun, MD, Timothy R. Billiar, MD, Melanie J. Scott, MD, PhD - University of Pittsburgh

 Discussant: Daniel L. Traber, PhD

49. MRSA CARRIER STATUS OF PATIENTS PRESENTING WITH SKIN AND SOFT TISSUE INFECTIONS

Carlos H. Palacio, MD, Daniel M. Musher, MD, Ricardo E. Nuila, MD, Anuradha Subramanian, MD, David M. Green, MD, BS, Samir S. Awad, MD - Baylor College of Medicine

 Discussant: Saman Arbabi, MD

50. MULTIDRUG-RESISTENT PATHOGENS AND INITIAL EMPIRIC ANTIBIOTIC THERAPY FOR PNEUMONIA IN THE TRAUMA VERSUS SURGICAL INTENSIVE CARE UNIT

Robert D. Becher, MD, Jason Hoth, MD, PhD, Lucas P. Neff, MD, Jerry J. Rebo, PharmD, Robert S. Martin, MD, Preston Miller, MD - Wake Forest University Medical Canter

 Discussant: Charles Adams, MD

51. SIGNIFICANT DIFFERENCES IN SERUM CYTOKINE LEVELS BETWEEN INFECTED ELDERLY AND YOUNGER ADULTS ADMITTED FOR CRITICAL CARE

Tjasa Hranjec, MD, MD, Brian R. Swenson, MD, MS, Lesly A. Dossett, MD, Rosemarie Metzger, MD, MPH, Laura H. Rosenberger, MD, Amani D. Politano, MD, Kimberly A. Popovsky, RN, Addison K. May, MD, Robert G. Sawyer, MD - University of Virginia

 Discussant: Raul Coimbra, MD, PhD

52. SPECTRUM OF PATHOGENS ASSOCIATED WITH INTRAABDOMINAL INFECTION AFTER PANCREAS TRANSPLANTATION WITH ENTERIC DRAINAGE

Christian Margreiter, MD, Natalie Berger, MD, Reinhold Kafka-Ritsch, MD, Raimund Margreiter, MD, Wolfgang Steurer, MD, Johann Pratschke, MD, Walter Mark, MD, Hugo J. R. Bonatti, MD - Surgery, Innsbruck Medical University

 Discussant: John Mihran Davis, MD

53. ORTHOPEDIC INJURIES-IT DOESN'T COME OUT IN THE WASH

Claudia E. Goettler, MD, Lisa Schlitzkus, MD, Scott G. Sagraves, MD, Christopher C. Hasty, MD, Michael F. Rotondo, MD - East Carolina University, Brody School of Medicine

 Discussant: Jeffrey Chipman, MD

54. PLATELET FACTOR 4 (PF4; CXCL4) PROMOTES REMOTE LUNG INJURY FOLLOWING MESENTERIC ISCHEMIA AND REPERFUSION

Peter H. Lapchak, MSc, PhD, Peter Karian, Poonam Rani, MSc, Lakshmi Kannan, PhD, Jurandir J. Dalle Lucca, MD, George C. Tsokos, MD - Beth Israel Deaconess Medical Center and Harvard Medical School

 Discussant: Charles H. Cook, MD

55. TWELVE-YEAR EXPERIENCE WITH SEVERE CANDIDA INFECTIONS: DECREASING MORTALITY, EVOLVING EPIDEMIOLOGY, AND EMERGENCE OF NEW ANTIFUNGALS

Carlos A. Tache Leon, MD, Tjasa Hranjec, MD, Swenson Brian, MD, Kimberly A. Popovsky, RN, Robert G. Sawyer, MD - University of Virginia

 Discussant: Annabel Barber, MD

56. BLADDER PRESSURE MEASUREMENTS ARE AN INDEPENDENT PREDICTOR OF UTI IN TRAUMA PATIENTS

Therese M. Duane, MD, Holly Brown, BS, Luke G. Wolfe, MS, Ajai K. Malhotra, MD, Michel B. Aboutanos, MD, MPH, Rao R. Ivatury, MD - Virginia Commonwealth University

 Discussant: Preston Roy Miller III, MD