— Of 1,000 consecutive patients undergoing fiberoptic bronchoscopy, 331 eventually were proven to have primary lung cancer. Of the 331 carcinomas, 253 were beyond the visual range of the flexible bronchoscope. However, under fluoroscopic guidance, the diagnosis of carcinoma was established in 194 (76.7%) of these nonvisualized tumors. Cytologic analysis of brush specimens was more often positive for malignancy than specimens obtained by forceps biopsy. An expert cytologist and experienced bronchoscopy team are essential for a high percentage of reliable positive diagnoses in bronchogenic carcinoma.
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References
1.
RabinCB: X-ray Diagnosis of Chest Disease. Baltimore, The Williams and Wilkins Company, 1952.
2.
JosephM: The protean manifestations of bronchial carcinoma. Med J Aust1: 745–750, 1965.
3.
GrungeH: Cytologic diagnosis of tumors of the chest. Acta Cytol (Baltimore)17: 148–159, 1973.
4.
DavisEWKatzSPeabodyJWJr: Surgical procedures in the diagnosis and treatment of bronchogenic carcinoma. Am J Roentgenol Radium Ther Nucl Med74: 429–436, 1955.
5.
SomnerARHillisBRDouglasAC: Value of bronchoscopy in clinical practice: A review of 1,109 examinations. Br Med J1: 1079–1084, 1958.
6.
IkedaS: Flexible bronchofiberscope. Ann Otol Rhinol Laryngol79: 916–923, 1970.
7.
RichardsonRHZavalaDCMukerjeeRK: The use of fiberoptic bronchoscopy and brush biopsy in the diagnosis of suspected pulmonary malignancy. Am Rev Respir Dis109: 63–66, 1974.
8.
BibboMFennessyJ JLuC: Bronchial brushing technique for the cytologic diagnosis of peripheral lung lesions: A review of 693 cases. Acta Cytol (Baltimore)17: 245–251, 1973.
9.
TeirsteinASChuangMMillerA: Application of the flexible bronchoscope. Mt Sinai J Med NY42: 81–94, 1975.
10.
SteeleD: The solitary pulmonary nodule. Report of a cooperative study of resected asymptomatic solitary pulmonary nodules in males. J Thorac Cardiovasc Surg46: 21–39, 1963.
11.
DaviesDF: A review of detection methods for the early diagnosis of lung cancer. J Chronic Dis19: 819–845, 1966.
12.
OswaldNCHinsonKFWCantiG: The diagnosis of primary lung cancer with special reference to sputum cytology. Thorax26: 623–631, 1971.
13.
FennessyJJ: Bronchial brushing. Ann Otol Rhinol Laryngol79: 924–932, 1970.
14.
KovnatDMRathGSAndersonWM: Maximum extent of visualization of ronchial tree by flexible fiberoptic bronchoscopy. Am Rev Respir Dis110: 88–90, 1974.
