The relationship among various malignant epithelial tumors of the larynx, with or without their respective lymph node and visceral metastases, is discussed. The tumors considered include squamous cell carcinoma, verrucous squamous cell carcinoma, spindle cell squamous carcinoma, small cell carcinoma, atypical carcinoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, and primary malignant melanoma. Other, rarer, malignant epithelial neoplasms of the larynx are only mentioned. The choice of therapy should be determined by tumor stage, oncotype, and patient status.
FerlitoA. Spread of cancer of the larynx. In: FerlitoA, ed. Cancer of the larynx. Vol. 2. Boca Raton, Fla: CRC Press, 1985: 109–41
2.
McGavranMHBauerWCOguraJH. The incidence of cervical lymph node metastases from epidermoid carcinoma of the larynx and their relationship to certain characteristics of the primary tumor. A study based on the clinical and pathological findings in 96 patients treated by primary en bloc laryngectomy and radical neck dissection. Cancer1961; 14: 55–66
3.
FerlitoA. Histological classification of larynx and hypopharynx cancers and their clinical implications. Pathologic aspects of 2,052 malignant neoplasms diagnosed at the ORL Department of Padua University from 1966 to 1976. Acta Otolaryngol [Suppl] (Stockh)1976:suppl 342
4.
SessionsDG. Surgical pathology of cancer of the larynx and hypopharynx. Laryngoscope1976; 86: 814–39
5.
FerlitoADi BonitoL. Primary cancer of the larynx associated with primary lung cancer. Report of 21 cases, 14 with autopsy findings and 7 biopsies. ORL J Otorhinolaryngol Relat Spec1976; 38: 230–45
6.
FerlitoARecherGVisonàA. Laryngeal cancer metastatic to lymph nodes with lymphocytic leukaemia. J Laryngol Otol1986; 100: 233–7
7.
KrausFTPerez-MesaC. Verrucous carcinoma: Clinical and pathologic study of 105 cases involving oral cavity, larynx and genitalia. Cancer1966; 19: 26–38
8.
Van NostrandAWPOlofssonJ. Verrucous carcinoma of the larynx. A clinical and pathologic study of 10 cases. Cancer1972; 30: 691–702
9.
BatsakisJGHybelsRCrissmanJDRiceDH. The pathology of head and neck tumors: Verrucous carcinoma. Head Neck Surg1982; 5: 29–38
10.
BillerHFOguraJHBauerWC. Verrucous cancer of the larynx. Laryngoscope1971; 81: 1323–9
11.
FerlitoAAntonuttoGSilvestriF. Histological appearances and nuclear DNA content of verrucous squamous cell carcinoma of the larynx. ORL J Otorhinolaryngol Relat Spec1976; 38: 65–85
12.
FerlitoARecherG. Ackerman's tumor (verrucous carcinoma) of the larynx. A clinicopathologic study of 77 cases. Cancer1980; 46: 1617–30
13.
SmithRRLKuhajdaFPHarrisAE. Anaplastic transformation of verrucous carcinoma following radiotherapy. Am J Otolaryngol1985; 6: 448–52
14.
AbramsonALBrandsmaJSteinbergBWinklerB. Verrucous carcinoma of the larynx. Possible human papillomavirus etiology. Arch Otolaryngol1985; 111: 709–15
15.
SchwadeJGWaraWMDedoHHPhillipsTL. Radiotherapy for verrucous carcinoma. Radiology1976; 120: 677–9
16.
BurnsHPvan NostrandAWPBryceDP. Verrucous carcinoma of the larynx: Management by radiotherapy and surgery. Ann Otol Rhinol Laryngol1976; 85: 538–43
17.
RiderWD. Toronto experience of verrucous carcinoma of the larynx. Can J Otolaryngol1975; 4: 278–9
18.
WangCC. Radiation therapy of laryngeal tumors. In: ThawleySEPanjeWRBatsakisJGLindbergRD, eds. Comprehensive management of head and neck tumors. Vol 1. Philadelphia: WB Saunders, 1987: 906–19
19.
FerlitoA. Malignant epithelial tumors of the larynx. In: FerlitoA, ed. Cancer of the larynx. Vol 1. Boca Raton, Fla: CRC Press, 1985: 91–196
20.
GneppDRFerlitoAHyamsV. Primary anaplastic small cell (oat cell) carcinoma of the larynx. Review of the literature and report of 18 cases. Cancer1983; 51: 1731–45
21.
FerlitoARecherGCarusoG. Primary combined small cell carcinoma of the larynx. Am J Otolaryngol1985; 6: 302–8
22.
FerlitoA. Diagnosis and treatment of small cell carcinoma of the larynx: A critical review. Ann Otol Rhinol Laryngol1986; 95: 590–600
23.
BaughRFWolfGTBealsTFKrauseCJForastiereA. Small cell carcinoma of the larynx: Results of therapy. Laryngoscope1986; 96: 1283–90
24.
FerlitoAPesaventoGRecherG. Long-term survival in response to chemotherapy and radiotherapy in laryngeal small cell carcinoma. Auris Nasus Larynx1986; 13: 113–23
25.
SnydermanCJohnsonJTBarnesL. Carcinoid tumor of the larynx: Case report and review of the world literature. Otolaryngol Head Neck Surg1986; 95: 158–64
26.
StanleyRJDeSantoLWWeilandLH. Oncocytic and oncocytoid carcinoid tumors (well-differentiated neuroendocrine carcinomas) of the larynx. Arch Otolaryngol1986; 112: 529–35
27.
GoldmanNCKatibahGMMedinaJ. Carcinoid tumors of the larynx. Ear Nose Throat J1985; 64: 130–4
28.
FerlitoARecherGBottinF. Mucoepidermoid carcinoma of the larynx. A clinicopathological study of 11 cases with review of the literature. ORL J Otorhinolaryngol Relat Spec1981; 43: 280–99
FerlitoAGaleNHvalaH. Laryngeal salivary duct carcinoma. A light and electron microscopic study. J Laryngol Otol1981; 95: 731–8
31.
ReuterVEWoodruffJM. Melanoma of the larynx. Laryngoscope1986; 94: 389–93
32.
KimHParkC. Primary malignant laryngeal melanoma. Report of a case with review of literature. Yonsei Med J1982; 23: 118–22
33.
FerlitoA, Primary lymphoepithelial carcinoma of the hypopharynx. J Laryngol Otol1977; 91: 361–7
34.
StanleyRJWeilandLHDeSantoLWNeelHBIII. Lymphoepithelioma (undifferentiated carcinoma) of the laryngohypopharynx. Laryngoscope1985; 95: 1077–81
35.
FerlitoA. Primary anaplastic giant cell adenocarcinoma of the larynx. J Laryngol Otol1976; 90: 1053–60
36.
FerlitoAFriedmannIRecherG. Primary giant cell carcinoma of the larynx. A clinicopathological study of four cases. ORL J Otorhinolaryngol Relat Spec1985; 47: 105–12
37.
PesaventoGFerlitoARecherG. Primary clear cell carcinoma of the larynx. J Clin Pathol1980; 33: 1160–4
38.
GerughtyRMHennigarGRBrownFM. Adenosquamous carcinoma of the nasal, oral and laryngeal cavities. A clinicopathologic survery of ten cases. Cancer1968; 22: 1140–55
39.
FerlitoA. Adenosquamous carcinoma of the larynx. A clinical and pathologic study. Report of four cases and review of the literature. Acta Otorhinolaryngol Belg1976; 30: 379–89
40.
CrissmanJDRosenblattA. Acinous cell carcinoma of the larynx. Arch Pathol Lab Med1978; 102: 233–6
41.
FerlitoA. Acinic cell carcinoma of the minor salivary glands. Histopathology1980; 4: 331–43
42.
HannaGSAliMH. Chemodectoma of the larynx. J Laryngol Otol1986; 100: 1081–7
