Abstract
Certain dermal appendage tumors have a striking histologic and clinical homology with some tumors arising from the salivary duct system. The dermal eccrine cylindroma is an exemplar. Arising from the eccrine ducts, this neoplasm is only occasionally found outside the head and neck, has a recurrence rate of over 40%, and in its malignant form is a high-grade carcinoma. Its counterpart in salivary glands the dermal analogue tumor, manifests a histologic similarity, if not identity, also has a relatively high recurrence rate, and can also undergo malignant change.
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References
1.
Crain
RC
Helwig
EB
. Dermal cylindroma (dermal eccrine cylindroma) . Am J Clin Pathol 1961 ; 35 : 505 –15 .
2.
Batsakis
JG
Brannon
RB
. Dermal analogue tumours of major salivary glands . J Laryngol Otol 1981 ; 95 : 155 –64 .
3.
Batsakis
JG
Brannon
RB
Sciubba
JJ
. Monomorphic adenomas of major salivary glands: A histologic study of 96 tumours . Clin Otolaryngol 1981 ; 6 : 129 –43 .
4.
Headington
JT
Batsakis
JG
Beals
TF
Campbell
TE
Simmons
JL
Stone
WD
. Membranous basal cell adenoma of parotid gland, dermal cylindromas, and trichoepitheliomas . Cancer 1977 ; 39 : 2460 –9 .
5.
Cotton
DWK
Braye
SG
. Dermal cylindromas originate from the eccrine sweat gland . Br J Dermatol 1984 ; 111 : 53 –61 .
6.
Weber
L
Wick
G
Gebhart
W
Krieg
T
Timpl
R
. Basement membrane components outline the tumour islands in cylindroma . Br J Dermatol 1984 ; 111 : 45 –51 .
7.
Cooper
PH
Frierson
HF
Morrison
AG
. Malignant transformation of eccrine spiradenoma . Arch Dermatol 1985 ; 121 : 1445 –8 .
