The Measurement of Serum Unsaturated Iron-Binding Capacity in the Presence of Iron-Dextran

The standard colorimetric methods most often used for the measurement of serum unsaturated iron binding capacity (UIBC) are subject to gross interference by iron dextran. This paper describes a brief evaluation of an alternative radiometric assay for serum UIBC, based on a commercially available kit method, but incorporating a modification to the manufacturer's protocol. The effects of iron dextran on the assay were determined.