New methods of investigation have enlarged understanding of the mechanisms underlying activity in the nervous system. Excitable cells transmit impulses by means of their special membrane properties and excitation is transmitted from cell to cell across specialized sites called synapses. In the nuclei of the central nervous system there are many small neurons that have no axon or only very short axons and dendrites. These are referred to as interneurons and the chemical transmitters they release may be excitatory or inhibitory to the cells with which they synapse. Cells with axons ending in a nucleus and cells with dendrites in the nucleus plus the interneurons which may intervene between the input of the message by an axon reaching the nucleus and its transmission onwards, form networks of cells that act as micro-circuits, affecting the nature of the neural signal. Control of transmission by these networks is the means by which sensory and motor impulses may be modified, enhanced, suppressed or facilitated. The integration of many sensory inputs, and the feedback during movement modulate and shape the motor response.
An understanding of the mechanisms of inhibition and facilitation becomes increasingly important for therapists who use techniques based on “sensori-motor integration“.
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