The growth promoting effects of thy roid gland may be observed in congeni tal thyrotoxicosis. The presence of ex cessive thyroid hormones appears to accelerate fetal development.
Rapid skeletal growth in the infant here described was striking and continued after a euthyroid state was established.
Get full access to this article
View all access options for this article.
References
1.
Danowski, T.S. , Johnston, S.Y., Price , W.C., Mc-Kelvy, M., Stevenson, S.S. and McClusky, E.R.: Protein-bound iodine in infants from birth to one year of age. Pediatrics7: 240, 1951.
2.
Farrehi, C., Mitchell, M. and Fawcett, D.M.: Heart failure in congenital thyrotoxicosis. Pediatrics37: 460, 1966.
3.
Dancis, J., O'Connell, J.R. and Holt, L.E.: A grid for recording the weight of premature infants. J. Pediat.33: 570, 1948.
4.
Woolley, P.V. , Jr. and Valdecanas , L.Q.: Growth of premature infants. A.M.A. J. Dis. Child.99: 642, 1960.
5.
Lesinski, J.: Relationship between length of gestation, birth weight and certain other factors, a statistical study. Bull. WHO26: 183, 1962.
6.
Spencer, R.P. : Relationship of fetal weight to the lunar month of pregnancy. Growth28: 91, 1964.
7.
Lubchenco, L.O. , Hansman, C., Dressler , M. and Boyd, E.: Intra-uterine growth as estimated from liveborn birth-weight data at 24 to 42 weeks of gestation . Pediatrics32: 793, 1963.
8.
Parmelee, A.H. , Jr., Stern, E., Chervin , G. and Minkowski, A.: Gestational age and the size of premature infants. Biol. Neonat.6: 309, 1964.
9.
Potter, E.L.: Pathology of the Fetus and Infant, 2nd Ed. Chicago, III., Year Book Medical Publishers , 1961, p. 11.
10.
Lubchenco, L.O., Hansman, C. and Boyd, E.: Intrauterine growth in length and head circumference as estimated from live births at gestational ages from 26 to 42 weeks. Pediatrics37: 403, 1966.
11.
Little, W.A. : The significance of placental/fetal weight ratios. Amer. J. Obstet. Gynec.79: 134, 1960.
12.
Gruenwald, P. and Minh, H.N.: Evaluation of body and organ weights in perinatal pathology II. Weight of body and placenta of surviving and autopsied infants. Amer. J. Obstet. Gynec.82: 312, 1961.
13.
Dekaban, A.: Neurology of Infancy. Baltimore, Md., The Williams and Wilkins Company, 1959, p. 42.
14.
Taylor, W.C. , James, J.A. and Henderson , J.L.: The significance of yellow vernix in the newborn. Arch. Dis. Child.27: 442, 1952.
15.
Eayrs, J.T.: Role of Thyroid Hormone in the Differentiation of the Nervous System . Proceedings of the Second International Congress of Endocrinology , London, 1964, Part II, International Congress Series No. 83, 1965, Excerpta Medica Foundation, p. 779.
16.
Pyle, S.I. and Hoerr, N.L.: Radiographic Atlas of Skeletal Developmental of the Knee. Springfield, III., Charles C Thomas, 1955, p. 35.
17.
Greulich, W.W. and Pyle, S.I.: Radiographic Atlas of Skeletal Development of the Hand and Wrist, 2nd Ed. Stanford, Calif., Stanford University Press , 1959, pp. 64, 74.
18.
Sunshine, P. , Kusumoto, H., Kriss , J.P., Pleshakov, V. and Chien, J.R.: Survival time of circulating long-acting thyroid stimulator in neonatal thyrotoxicosis: implications for diagnosis and therapy of the disorder. Pediatrics36: 869, 1965.
19.
Glass, S.D. , Townsley, J.T. and Geppert, L.J.: Neonatal hyperthyroidism. J. Pediat.64: 906, 1964.
20.
Paatela, M. : Neonatal thyrotoxicosis. Ann. Paediat. Fennioe.6: 309, 1960.
21.
Expert Group on Prematurity, Final Report. World Health Organization, Technical Report Series 27: 3, 1950.
22.
Grumbach, M.M. and Werner, S.C.: Transfer of thyroid hormone across the human placenta at term. J. Clin. Endocr.16: 1392, 1956 .
23.
Hodges, R.E. , Evans, T.C., Bradbury , J.T. and Keettel, W.C.: The accumulation of radioactive iodine by human fetal thyroids. J. Clin. Endocr.15: 661, 1955.
24.
Boyd, J.D.: Development of the human thyroid gland. In The Thyroid , Vol. 1. Ed. by Pitt-Rivers, R. and Trotter, W. R.London, Butterworths, 1964, p. 9.
Tata, J.R.: Thyroid Hormones and Regulation of Protein Synthesis. Proceedings of the Second International Congress of Endocrinology , London, 1964, Part I, International Congress Series No. 83, 1965, Excerpta Medica Foundation, p. 46.
27.
Sokoloff, L. : The Action of Thyroid Hormones on Protein Synthesis, as Studied in Isolated Preparations and in the Whole Rat. Ibid., p. 87.