Malacoplakia in the head and neck is uncommon, and malacoplakic lesions involving the thyroid are extremely rare. The author describes the case of a 64-year-old woman who developed malacoplakia at the site of a previous total thyroidectomy. The disease manifested as a chronic inflammatory mass beneath a persistently discharging surgical wound site, and it prevented the incision from healing. Diagnosis was based on a thorough histopathologic analysis.
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