The design, construction and fabrication of a high frequency needle-based ultrasound imaging system is described. A miniature lead zirconate titanate transducer was mounted opposite a parabolic mirror in a stainless steel needle. By inserting the needle into a tissue, a cross section image of the tissue can be made. Two needle probes were built, a 45 MHz 2.8 mm diameter probe with 125 μm lateral, 55 μm axial resolution and a 55 MHz 1.6 mm diameter probe with 105 μm lateral, 40 μm axial resolution. Preliminary phantom and in vitro tissue images demonstrate the feasibility of high frequency needle-based imaging.
BomN.SlagerC. J.Van EgmondF. C.LancéeC. T.SemiysP. W., Intraarterial ultrasonic imaging for recanalization by spark erosion, Ultrasound Med. Biol.14, 257–261 (1988).
2.
YockP. G.LinkerD. T.ThapilyalH. V.ArensonJ. W.SamstadS.SaetherO.AngelsenB. A. J., Real-time, two-dimentional catheter ultrasound: A new technique for high resolution intravascular imaging, J. Am. Coll. Cardiol.11, 130A (abstract) (1988).
HodgsonJ.EberleM.SavakusA., Validation of a new real-time percutaneous ultrasound intravascular imaging catheter, Circulation78, II–22 (abstract) (1988).
5.
AretzH. T.MartinelliM. A.LeDetE. G., Intraluminal ultrasound guidance of transvers laser coronary atherectomy, Int. J. Card. Imaging4, 153–157 (1989).
6.
NevilleR. F.BarotelliA. L.SidawyA. N.AlmagorY.PotkinB.LeonM. B., An in vivo feasibility study of intravascular ultrasound imaging, Am. J. Surgery158, 142–145 (1989).
7.
GoldbergB. B.LiuJ.MertonB. S.KurtzA. B., Endoluminal US: Experiments with nonvascular uses in animals, Radiology175, 39–43 (1990).
8.
MartinR. W.SilversteinF. E.KimmeyM. B., A 20-MHz ultrasound system for imaging the intestinal wall, Ultrasound Med. Biol.15, 273–280 (1989).
9.
GussenhovenE. J.EssedC. E.LancéeC. T.MastikF.FrietmanP.VanEgmondF. C.ReiberJ.BoschH.VanUrkH.RoelandtJ.BomN., Arterial wall characteristics determined by intravascular ultrasound imaging: an in vitro study, J. Am. Coll. Cardiol.14, 947–952 (1989).
10.
LockwoodG. R.HuntJ. W.FosterF. S., The design of protection circuitry for high frequency ultrasound imaging systems, IEEE Trans. Ultrason. Ferroelec. Freq. Contr.38, 48–55 (1991).
11.
FosterF. S.RyanL. K.TurnbullD. H., Characterization of lead zirconate titanate ceramics for use in miniature high frequency (20–80 MHz) transducers, IEEE Trans. Ultrason. Ferroelec. Freq. Contr.38, 446–453 (1991).
12.
LockwoodG. R., High Frequency Ultrasound Imaging with Applications to Intravascular Imaging, Ph.D. Thesis, Department of Medical Biophysics, University of Toronto, pp. 41–50 (1992).
13.
LockwoodG. R.RyanL. K.GotliebA. I.LonnE.HuntJ. W.LiuP.FosterF. S., In vitro high resolution intravascular imaging in muscular and elastic arteries, J. Am. Coll. Cardiol.20, 153–160 (1992).
14.
LockwoodG. R.RyanL. K.HuntJ. W.FosterF. S., Measurement of the ultrasonic properties of vascular tissues and blood from 35 to 65 MHz. Ultrasound Med. Biol., 17, 653–666 (1991).
15.
YanoT.FukukitaH.UenoS.FukumotoA., 40 MHz Ultrasound diagnostic system for dermatologic examination, 1987 IEEE Ultrason. Symp. Proc., pp. 875–878, (IEEE Cat. No. 87CH 2492-7).
16.
PavlinC. J.SherarM. D.FosterF. S., Subsurface ultrasound microscopic imaging of the intact eye, Ophthalmology97, 244–250 (1990).
17.
PavlinC. J.HarasiewiczK. A.SherarM. D.FosterF. S., Clinical use of ultrasound biomicroscopy, Ophthalmology98, 287–295 (1991).
