Recruiting participants for research studies is often a challenging task. Recruitment requires careful planning, collaboration, and flexibility on the part of researchers and health care providers at the recruitment sites. This article describes six major barriers to recruiting study participants as identified from a review of the literature and from the coauthors' research experiences. These barriers include challenges related to regulations of the Health Insurance Portabililty and Accountability Act (HIPAA), health care providers' work burden, providers' financial disincentives, competition, health care provider concerns regarding research, and provider protection of patients. Each barrier is described, and specific strategies are suggested based on the empirical literature. In some instances, the coauthors' experiences are also shared.
Arford, P. (2004). Working with human research protections. Journal of Nursing Scholarship, 36, 265-271.
2.
Breese, P., Burman, W., Rietmeijer, C., & Lezotte, D. (2004). The Health Insurance Portability and Accountability Act and the informed consent process. Annals of Internal Medicine , 141, 897-898.
3.
Brooker, C., Peters, J., McCabe, C., & Short, N. (1999). The views of nurses to the conduct of a RCT of problem drinkers in an accident and emergency department. International Journal of Nursing Studies, 36, 33-39.
4.
Burge, S., Scheider, F., Ivy, L., & Catala, S. (2005). Patient's advice to physicians about intervening in family conflict. Annals of Family Medicine, 3, 248-254.
5.
Butterfield, P., Yates, S., Rogers, B., & Healow, J. (2003). Overcoming subject recruitment challenges: Strategies for successful collaboration with novice research agencies. Applied Nursing Research, 16, 46-52.
6.
Cody, W.K. (2003). Paternalism in nursing and health care: Central issues and their relation to theory. NursingScience Quarterly , 16, 288-296.
7.
Erlen, J. (2005). HIPAA-Implications for research. Orthopedic Nursing, 24, 139-142.
8.
Goodrich, C., & Ward, C. (2004). Evaluation and revision of a clinical advancement program. Medsurg Nursing, 13, 391-398.
9.
Handron, D. (1992). Research basics: Getting past gatekeepers. Decubitus, 5, 52-54.
10.
Holder, B., Turner-Musa, J., Kimmel, P., Alleyne, S., Kobrin, S., Simmens, S., et al. (1998). Engagement of African-American families in research on chronic illness: A multisystem recruitment approach. Family Process, 37, 127-151.
11.
Institute of Medicine. (2001). Crossing the quality chasm: A new health system for the 21st century. Washington, DC: National Academy Press.
12.
Kaiser, J. (2004). Privacy rule creates bottleneck for U.S. biomedical researchers. Science, 305, 168-169.
13.
Kerlinger, F.N. (1992). Foundations of behavioral research. Fort Worth, TX: Harcourt.
14.
Ness, R. (2005). A year is a terrible thing to waste: Early experiences with HIPAA. Annals of Epidemiology, 15, 85-86.
15.
Olsen, D.P. (2003). HIPAA privacy regulations and nursing research . Nursing Research, 52, 344-348.
16.
Rose, K. (2000). Gaining access to potential research participants . Professional Nurse, 15, 465-467.
17.
Somkins, C., Altschuler, A., Ackerson, L., Geiger, A., Greene, S., Nelson, A., et al. (2005). Organizational barriers to physician participation in cancer clinical trials. AmericanJournal of Managed Care , 11(7), 413-421.
18.
Sullivan-Bolyai, S., Grey, M., Deatrick, J., Gruppuso, P., Giraitis, P., & Tamborlane, W. (2004). Helping other mothers effectively work at raising young children with type 1 diabetes. Diabetes Educator, 30, 476-484.
19.
Thomas, C., Pinto, H., Roach, M., & Vaughn, C. (1994). Participation in clinical trials: Is it state-of-the-art treatment for African-Americans and other people of color? Journal of the National Medical Association, 86, 177-182.
20.
U.S. Department of Health and Human Services. ( 1996). Are you a covered entity (last amended December 2005) . Retrieved August 15, 2006, from http://www.cms.hhs.gov/HIPAAGenInfo/06_AreYouaCoveredEntity.asp
21.
U.S. Department of Health and Human Services. ( 2001a). Title 21: Food and Drugs. Code of federal regulations 56.107. Retrieved August 23, 2006, from http://a257.g.akamaitech.net/7/257/2422/04nov20031500/edocket.access.gpo.gov/cfr_2001/aprqtr/21cfr56.107.htm
22.
U.S. Department of Health and Human Services. ( 2001b). Title 45: Public Welfare. Code of federal regulations 164.512. Retrieved August 23, 2006, from www.access.gpo.gov/nara/cfr/waisidx_02/45cfrl64_02.html
23.
van Ryn, M., & Burke, J. (2000). The effect of patient race and socio-economic status on physician's perceptions of patients, Social Science and Medicine, 50, 813-828.
24.
Walson, P. (1999). Patient recruitment: U.S. perspective. Pediatrics, 104 Supplement, 619-622.
25.
Weaver Moore, L., & Miller, M. (1999). Initiating research with doubly vulnerable populations . Journal of Advanced Nursing, 30, 1034-1040.
26.
Wilson-Barnett, J., & Griffiths, P. (2002). The disappearing sample: Researcher and research ability. International Journal of Nursing Studies, 39, 365-367.
