Autogenous mandibular grafts that have been cryosurgically devitalized and reimplanted have been studied in the canine. Initial investigations have lent impetus to further application in human cancer surgery. Six patients underwent immediate autogenous mandibular graft reconstruction. All failed because of intraoral complications and decreased vascularization in the midportion of the bone graft. None evidenced recurrence of tumor in bone, although two patient's grafts failed on the basis of tumor recurrence in the adjacent soft tissue.
Get full access to this article
View all access options for this article.
References
1.
CummingsCW: Experimental observations of canine mandibular regeneration subsequent to freezing. Ann Otol Rhinol Laryngol, 1979.
2.
LeipzigBWaguespackRWCummingsCW: Experimental observations of canine mandibular regeneration subsequent to freezing. Ann Otol Rhinol Laryngol, to be published, 1981.
3.
LeipzigBCummingsCWChungCT: Canine mandibular regeneration subsequent to freezing: Effects of adding bone marrow and of irradiation. Proceedings of the Third International Symposium on Plastic and Reconstructive Surgery of the Head and Neck, vol 2, 1981.
4.
LeipzigBCummingsCW: Replacement of tumor involved mandible by a cryosurgically devitalized autograft: Human experience. Arch Otolaryngol106: 252–255, 1980.
5.
WeaverAWSmithDB: Frozen autogenous mandibular stent-graft for immediate reconstruction in oral cancer surgery. Am J Surg126: 505–506, 1973.
PopescuVSuperscuIE: Bone resection extra-corporal cryotherapy and immediate re-implantation in the treatment of mandibular tumors. J Maxillofac Surg8: 8–16, 1980.
