The maximum velocity gain of smooth pursuit and optokinetic, vestibular, and optovestibular slow phases was examined in 15 patients with pontine, 10 with medullary, 10 with cerebellar, and 5 with combined cerebello — brain stem disorders. Marked dissociations were observed between smooth pursuit and optokinetic slow phases, especially in medullary disease. A cerebellar deficit enhanced slow phase velocity gain during rotation in darkness, whereas the corresponding gain during rotation in light was normal.
Get full access to this article
View all access options for this article.
References
1.
BalohRWHonrubiaVSillsA: Eye-tracking and optokinetic nystagmus: Results of quantitative testing in patients with well-defined nervous system lesions. Ann Otol Rhinol Laryngol86: 108, 1977.
2.
WennmoC: Eye movements in posterior fossa disorders: An electro-oculographic study. Thesis, University of Lund, Sweden, 1982.
3.
Ter BraakJWG: Untersuchungen ueber optokinetischen Nystagmus. Arch Phys21: 309–376, 1936.
4.
HonrubiaVDowneyWLMitchellDPWardPH: Experimental studies on optokinetic nystagmus. II. Normal humans. Acta Otolaryngol65: 441–448, 1968.
5.
BarmackNH: Visually evoked activity of neurons in the dorsal cap of the inferior olive and its relationship to the control of eye movements.InBakerRBerthozA editors: Control of gaze by brain stem neurons: Developments in neuroscience, vol 1. Amsterdam, 1977, Elsevier/North Holland Biomedical Press, pp 361–370.
6.
PrechtWStrataP: On the pathway mediating optokinetic responses in vestibular nuclear neurons. Neuroscience5: 777–787, 1980.
7.
WennmoCHindfeltBPyykköI: Eye movements in cerebellar and combined cerebello-brainstem diseases. Ann Otol Rhinol Laryngol (In press).
8.
BalohRWYeeRDKimmJHonrubiaV: Vestibular-ocular reflex in patients with lesions involving the vestibulocerebellum. Exp Neurol72: 141–152, 1981.
9.
CourjonJHJeannerodMFlandrinJMSchmidR: Effects of unilateral floccular lesions on the vestibulo-ocular reflex in the cat.InBakerRBerthozA editors: Control of gaze by brain stem neurons: Developments in neuroscience, vol 1. Amsterdam1977, Elsevier/North-Holland Biomedical Press, pp 409–415.
10.
HonrubiaV: Optokinetic nystagmus.InSchmidRZambarbieriD editors: Eye movement analysis in neurological diagnosis. Center of Bioengineering, Pavia, Italy, 1979, University of Pavia, pp 71–96.
11.
KellerELCrandallWF: Neural activity in the nucleus reticularis tegmenti pontis in the monkey related to eye movements and visual stimulation.InCohenB editor: Vestibular and oculomotor physiology: International meeting of the Bárány Society, vol 374. New York, 1981, New York Academy of Sciences, pp 249–261.
12.
ZeeDSYamazakiAGucerG: Ocular motor abnormalities in trained monkeys with floccular lesions. Soc Neurosci Abstr4: 168, 1978.
13.
KellerELPrechtW: Visual-vestibular responses in vestibular nuclear neurons in the intact and cerebellectomized, alert cat. Neuroscience4: 1599–1613, 1979.
