Joint surgical associations (EACTS,LACES,ASCVTS,AATS,and STS) position statement regarding the VARC-3 definitions for aortic valve clinical research

Abstract

Get full access to this article

View all access options for this article.

References

Généreux

Piazza

Alu

, et al.; VARC-3 Writing Committee. Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research. Eur Heart J. 2021; 42: 1825–1857.

European Medicines Agency. ICH E9 statistical principles for clinical trials. Accessed August 30, 2021. https://www.ema.europa.eu/en/ich-e9-statistical-principles-clinical-trials.

Popma

Deeb

Yakubov

, et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med 2019; 380: 1706–1715.

Mack

Leon

Thourani

, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med 2019; 380: 1695–1705.

Makkar

Thourani

Mack

, et al. Five-year outcomes of transcatheter or surgical aortic-valve replacement. N Engl J Med 2020; 382: 799–809.

Stone

Serruys

Sabik

. PCI or CABG for left main coronary artery disease (Author Reply). N Engl J Med 2020; 383: 292–294.

Gregson

Stone

Ben-Yehuda

, et al. Implications of alternative definitions of peri-procedural myocardial infarction after coronary revascularization. J Am Coll Cardiol 2020; 76: 1609–1621.

Hara

Serruys

Takahashi

, et al. Impact of peri-procedural myocardial infarction on outcomes after revascularization. J Am Coll Cardiol 2020; 76: 1622–1639.

Regueiro

Abdul-Jawad Altisent

Del Trigo

, et al. Impact of new-onset left bundle branch block and periprocedural permanent pacemaker implantation on clinical outcomes in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis. Circ Cardiovasc Interv 2016; 9: e003635.