Dynamics of the Iodine-goitrogen Balance in the Thyroid Status of Catfish from Selected Fresh and Brackish Water Bodies

Abstract

The study was designed to investigate the dynamics of the goitrogen-iodine balance in Igbokoda brackish and Ogbese fresh water bodies in Ondo State, Nigeria. The parameters determined include iodine, thiocyanate, chloride, nitrate, calcium, magnesium hardness, calcium hardness, total hardness, and total coliform counts in water, sediment and/or fish (flesh and serum). The fish were subjected to a number of treatments (boiling with water or sodium chloride solution, frying or roasting) prior to analysis. The iodine level (μg I/100g) in the flesh of fish varied with size, treatment and location; it increased with size, was reduced by some treatments (boiling with either water or NaCl solution), while frying and roasting did not affect the level. The least values were 93.45 (Ogbese fish boiled with NaCl solution) and 160.94 (Igbokoda fish boiled with either water or NaCl solution). On the whole, Igbokoda (160.94–314.08) had higher values than Ogbese (93.45–205.06). Serum iodine (μg I/100mL) was equally higher in Igbokoda (5.00–9.00) compared to Ogbese (2.80–5.00). Only the large sized fish of Ogbese recorded a value of 5.00 μmol/L for thiocyanate while this parameter was not detected in other samples. The calculated I/goitrogen ratios (I/Ca, I/NO₃, I/Cl and I/SCN) were higher for Igbokoda water than Ogbese water with the exception of I/Mg. This was equally reinforced by the total count of coliforms (goitrogenic), which was higher in Ogbese (3.0 × 10³) than in Igbokoda (2.7 × 10³). These results indicate that the Igbokoda brackish water body would be a better source of iodine than Ogbese fresh water body for the population dependent on them.

Keywords

Iodine Goitrogens Fresh water Brackish water

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References

Akindahunsi

A.A.

(1992). A study of the chemical causes of goitre in Akoko and Ilesha areas of South-Western Nigeria. PhD thesis, Obafemi Awolowo University, Ile-Ife, 78–94.

American Public Health Association . (1992). Standard methods for the examination of water and water waste, New York, 210.

Anderson

R.H.

Maxwell

D.I.

Mulley

A.E.

Fritsch

C.W.

(1976). Effect of processing and storage on micronutrients in breakfast cereals. Food Technology, 30(5), 110–115.

Belling

G.B.

(1983). Further studies on the recovery of iodine-125 after alkaline ashing prior to assay. The Analyst, London, 108,763–765.

Brown

Seyfarth

Brown

R.C.

(1989). A twelve year follow-up of iodine deficiency in Bulape, Zaire. Annales De La Societe Belge De Medicine Tropicale, 69, 251–255.

Cavalieri

R.R.

(1980). Trace Element: Iodine. In: modern nutrition in health and disease (6th Edition) ( Goodhardt

R.S.L.

ed.) 395–407 Febriger, Philadelphia, US.

Clugston

G.A.

Hetzel

B.S.

(1994). Iodine. In: modern nutrition in health and diseases ( Shils

M.E.

Olson

J.A.

Shike

Eds.), Vol. 12, 8th ed, 252–263.

Das

S.C.

Isichei

U.P.

Egbuta

J.O.

Banwo

A.I.

(1989). Cations and anions in drinking water as putative contributory factors to endemic goiter in Plateau State, Nigeria. Tropical Geography and Medicine, 41, 346–352.

Fawole

M.O.

Oso

B.O.

(1995). Laboratory manual on microbiology, 2nd edn. Spectrum Books Ltd., Ibadan, Nigeria, 77–78.

10.

Gaitan

(1983). Role of other naturally occurring goitrogens in the etiology of endemic goitre. In: Cassava toxicity and the thyroid: research and public health issues ( Dellange

Ahluwalia

, eds). IDRS-207e Ottawa, Canada, 27–34.

11.

Gaitan

(1990). Goitrogens in food and water. Annual Review of Nutrition, 21–39.

12.

Hamre

Lie

Mage

Juisham

(1995). Final report Norwegian science foundation. Project of Norway Institute of Nutrition, Directorate of Fisheries, Bergen, Norway.

13.

Harrison

M.T.

(1965). Iodine balance studies and the availability of Iodine. Proceeding of The International Thyroid Conference, Rome, 241–248.

14.

Hetzel

B.S.

Dunn

J.T.

(1989). The iodine deficiency disorders; their nature and prevention. Annual Review of Nutrition, 9, 21–38.

15.

Hunn

J.B.

Fromm

P.O.

(1996). In vivo uptake of radio iodide—by rainbow trout. Journal of Water Pollution and Control Fed. 38, 1981–1985.

16.

Hunt

D.W.C

Eales

J.G.

(1979). Iodine balance of rainbow trout (Salmo gaidneri) and effect of testosterone propionate. Journal of Fish Resources Board of Canada, 36, 282–285.

17.

Jacob

S.S.

(1982). Osmotic regulation in Chrisichthys nigrodigitatus and clarias isheriensis . MSc dissertation, University of Lagos.

18.

Joint Expert Committee on Food Additives (JECFA) . (1989). WHO Food Additives Series, no.24. WHO, Geneva, 3–42.

19.

Karen

M.E.

Amund

(1997). Iodine content in fish and other food products from East Africa Journal of Food Composition and Analysis, 10,270–272.

20.

Kidd

(1974). Iodine Content of fish and other marine product. National Academy of Science, Washington, DC, pp. 1–23.

21.

Kusic

Simunic

E.M.

Davovic

Rak

Kukinac

Spaventi

(1990). Endemic goiter with adequate iodine intake, Lancet, 335, 1229–1230.

22.

Lambert

J.L.

Hatch

G.L.

Mosier

(1975). Iodide and iodine determination in parts per billion range with leucocrystal violet and N-chlorosuccinimide-succinimide reagents. Analytical Chemistry, USA, 47(6), 915–916.

23.

Lui

D.R.

C.Y.

Zhang

P.Y.

Quian

Q.D.

Zhang

C.D.

Jia

Q.Z.

Wang

H.X.

Eaestman

C.J.

Boyages

C.S.

(1987). Endemic goitre in central China caused by excessive iodine -intake, Lancet, 257–259.

24.

Lindsay

R.H.

(1997). Anti-thyroid effect of coal-derived pollutants. Journal of Toxicology and Environmental Health, 37, 467–481.

25.

Mahesh

D.C.

Deosthale

Y.G.

Narasinga-Rao

B.S.

(1992). A sensitive kinetic assay for the determination of iodine in foodstuff. Food Chemistry, 43, 51–56.

26.

Monday

J.R.

Lindstorm

(1977). Selection of plastic containers for storage of trace element samples. Analytical Chemistry, Washington, 49, 2264–2267.

27.

Parker

R.C.

(1972). Water Analysis by Atomic Absorption Spectrophotometer, Varian Techron Switzerland, pp. 32.

28.

Elmer

Perkin

, (1982). Analytical Methods for Atomic Absorption Spectrophotometer. Perkin Elmer Corp., USA.

29.

Pettigrew

A.R.

Fell

G.S.

(1972). Simplified colorimetric determination of thiocyanate in biological fluids and its application to investigation of the toxic amplyopias. Clinical Chemistry, USA, 18(9),995–1000.

30.

Powell-Jackson

P.R.

Day

T.K.

(1972). Fluoride, water hardness and endemic goitre. The Lancet, 1135–1138.

31.

Seffner

(1995). Natural-water ingredients and endemic goitre. Zentralblatt Fur Hygiene Und Umweltmedizin, 196(5), 381–398.

32.

Siakpere

O.K.

(1985). Hematological characteristics of Clarias isherinsis . Journal of Fish Biology. 27, 259–263.

33.

Sreemuramulu

Suryanarayana-Rao

S.V.

(1992). Distribution of iodine in marine food from different region of India. India Journal of Medical Resources. 96, 168–170.

34.

Svobodova

Frauda

Palackova

(1991). Unified methods of heamatological examination offish. Research institute of fish culture and hydrobiology, Czechoslovakia, pp. 331.

35.

Ubom

G.A.

Noda

(1987). Goitre and water factor relationship. In ( Takahashi

Anekwe

G.E.

Eds). Proceedings Nigerian/Japan Joint Conference of Trace Metal, Diarrhea, Goitre, Medical Entomology and Epidemiology Studies, Ehindero publishers, Jos, Nigeria, 68–69.

36.

Ubom

G.A

(1991). The goitre-soil-water-diet-relationship. Case study in Plateau State, Nigeria. The Science of the Total Environment, 107, 1–11.

37.

Underwood

E.J.

(1977). Iodine. In: Trace elements in human and animal nutrition, 4th edn., Academic press, New York, chapter 11 43–57.

38.

Wang

L.F.

Wang

H.M.

Lin

F.F.

Sun

X.F.

M.Y.

Lin

Feng

Z.Y.

Fan

Q.X.

(1986). A preliminary investigation of endemic goitre on the inclined plain in front of the Tianshian Mountains in Kuitun-Usum area. Clinical Medicine Journal, 99, 673–678.

39.

World Health Organization . (1982). Guidelines for Drinking Water Quality, Geneva. 1–34.