Computer Simulations in Teaching Neuromuscular Pharmacology—Time for a Change from Traditional Methods?

Two interactive computer programs are described which illustrate different approaches to teaching the pharmacology of neuromuscular transmission. Both programs are based on a simulation of the in vivo sciatic nerve–tibialis anterior muscle preparation of the cat. Program 1 simulates the preparation and allows students to follow a schedule set by the teacher, or design experiments themselves using drugs (including unknowns) and procedures selected from an extensive menu. The sequence of events and the doses used are entirely in the hands of the user and students “learn by discovery”. Program 2 is an interactive, computer-assisted learning package based on a software simulation of experiments which can be performed on this preparation to illustrate the fundamental pharmacology. The program is menu-driven, contains extensive textual information, makes use of animated graphics, and is accompanied by educational support material and assessments. Details of each program are presented and their use as alternatives to animal experiments is discussed in relation to the primary teaching objectives of practical classes.