Switching antipsychotics. Antipsychotic tolerance,withdrawal and relapse: unresolved issues and research implications

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Aceto M. (1990) Assessment of physical dependence techniques for the evaluation of abused drugs. In Adler M W , Cowen A (eds), Testing and evaluation of drugs of abuse. Willey-Liss, New York, pp. 67-79

Aranko K. , Mattila J. , Nuutila A. , Pellinen J. (1985). Benzodiazepines, but not antidepressants or neuroleptics, induce dose-dependant tolerance to lorazepam in psychiatric patients. Acta Psychiatr Scand 72: 436-46

Baldessarini R. , Viguera A. , Tondo L. (1999a) Discontinuing psychotropic agents. J Psychopharmacol 13: 292-3

Baldessarini R. , Tondo L. , Viguera A. (1999b) Discontinuing lithium maintenance treatment in bipolar disorder: Risks and implications. Bipolar Disorders 1: 17-24

Chue P. , Stip E. , Remington G. , Kopala L. (2004) Switching antipsychotics: a review. Acta Neuropsychiatr 16: 301-13

Davis J. , Marder S. , Tamminga C. (2006) Switch or stay? Am J Psychiatry 163: 2032-3

Essock S. , Covell N. , Davis S. , Stroup T. , Rosenheck R. , Lieberman J. (2006) Effectiveness of switching antipsychotics. Am J Psychiatry 163: 2090-5

Fernandez H. , Trieschmann, M. , Okun M. ( 2005) Rebound psychoses: Effect of discontinuation of antipsychotics in Parkinson's disease. Movement Disorders 20: 104-15

Gerlach J. , Koppelhus P. , Helweg E. , Manrad A. (1974) Clozapine and haloperidol in a single-blind cross-over trial. Therapeutic and biochemical aspects in the treatment of schizophrenia . Acta Psychiatr Scand 50: 410-24

10.

Goudie A. (2000) What is the clinical significance of the discontinuation syndrome seen with clozapine? J Psychopharmacol 14: 188-92

11.

Goudie A. , Smith J. , Robertson A. , Cavanagh C. (1999) Clozapine as a drug of dependence. Psychopharmacology 142: 369-74

12.

Goudie A. , Cooper G. , Cole J. , Sumnall H. (2007a) Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats. J Psychopharmacol 21: 171-90

13.

Goudie A. , Cole J. , Sumnall H. (2007b) Olanzapine and JL 13 induce cross-tolerance to the clozapine discriminative stimulus in rats. Behav Pharmacol 18: 9-17

14.

Goudie A. , Cole J. , Sumnall H. (2007c) Olanzapine withdrawal/discontinuation-induced hyperthermia in rats. Progress in Neuropsychopharmacology and Biological Psychiatry 31: 1500-03

15.

Grassi B. , Ferrari R. , Epifani M. , Dragoni C. , Cohen S. , Scarone S. (1999) Clozapine lacks previous clinical efficacy when restarted after a period of discontinuation: a case series. Eur Neuropsychopharmacol 9: 479-81

16.

Haro J, Novick D, Belger M, Jones P, SOHO Advisory Board (2006) Antipsychotic type and correlates of antipsychotic treatment discontinuation in the outpatient treatment of schizophrenia. Eur Psychiatry 21: 41-7

17.

Lieberman J. , Stroup T. , McEvoy J. , Swartz M. , Rosenheck R. , Perkins D. , Keefe R. , Davis S. , Davis C. , Lebowitz B. , Severe J. , Hsiao J. (2005) Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England J Med 353: 1209-23

18.

Llorca P. , Vaiva G. , Lancon C. (2001) Supersensitivity psychosis in patients after sudden olanzapine withdrawal. Can J Psychiatry 46: 87-8

19.

Margolese H. , Chouinard G. , Beauclair L. , Bellanger M-C. (2002) Therapeutic tolerance and rebound psychosis during quetiapine maintenance monotherapy in patients. J Clin Psychopharmacol 20: 489-90

20.

Meltzer H. , Lee M. , Ranjan R. , Mason E. , Cola P. ( 1996). Relapse following clozapine withdrawal. Psychopharmacology 124: 176-87

21.

Miodownik C. , Lerner V. , Kibari A. , Toder D. , Cohen H. (2006) The effect of sudden clozapine discontinuation on management of schizophrenic patients: a retrospective controlled study . J Clin Psychiatry 67: 1204-8

22.

National Collaborating Centre for Mental Health ( 2003) Full national clinical guidelines on core interventions in primary and secondary care for schizophrenia. Gaskell and British Psychological Society, London and Leicester, ISBN 1-901242-97- 8

23.

Nayudu S. , Scheftner W. (2000) Case report of withdrawal syndrome after olanzapine discontinuation. J Clin Psychopharmacol 20: 489-90

24.

Sabuncuoglu O. (2007) Risperidone to methylphenidate switch reaction in children: three cases. J Psychopharmacol 21: 216-9

25.

Samaha A. , Seeman P. , Stewart J. , Rajabi H. , Kapur S. (2007) "Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time. J Neuroscience 27: 2979-86

26.

Seppala N. , Kovio C. , Leinonen E. (2005) Effects of anticholinergic drugs in preventing acute deterioration in patients undergoing abrupt clozapine withdrawal. CNS Drugs 19: 1049-55

27.

Tollefson G. , Dellva M. , Mattler C. , Kane J. , Wirshing D. , Kinon B. (1999) Controlled double-blind investigation of clozapine discontinuation symptoms with conversion to either olanzapine or placebo. J Clin Psychopharmacol 19: 435-43

28.

Viguera A. , Baldessarini R. , Hegarty J. , Van Kammen D. , Tohen M. (1997) Clinical risk following abrupt and gradual withdrawal of maintenance neuroleptic treatment. Arch Gen Psychiatry 54: 49-55

29.

Weiden P. (2006) Switching antipsychotics: an updated review with a focus on quetiapine. J Psychopharmacol 20: 104-8