Twenty-three mares were infected with contagious equine metritis organism by intrauterine inoculation, and necropsied after intervals of two to 116 days. Severe diffuse subacute salpingitis was seen in one mare, and mild multifocal subacute salpingitis was common. Severe diffuse endometritis and cervicitis initially were acute and became more severe, subacute and predominantly plasmacytic by 14 days, then declined but persisted as mild diffuse or multifocal inflammation for the rest of the experimental period. Vaginitis arose in parallel but resolved after 70 days. There were no lesions in the clitoral fossa or clitoral sinus.
References
1.
AclandH.M.AllenP.Z.KenneyR.M.:
Contagious equine metritis: distribution of organisms in experimental infection of mares.
Am J Vet Res
(Accepted for publication).
2.
CallisJ.J.DardiriA.H.FerrisD.H.GayJ.MasonJ.WilderF.W.:
Illustrated Manual for the Recognition and Diagnosis of Certain Animal Diseases,
5th ed.,
pp. 66–68.
U.S. Dept of Agriculture,
Greenport, NY,
1981.
3.
KenneyR.M.:
Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on an early embryonic death.
J Am Vet Med Assoc172:
241–262,
1978.
4.
PiersonR.E.SahuS.P.DardiriA.H.WilderF.W.:
Contagious equine metritis: clinical description of experimentally induced infection.
J Am Vet Med Assoc173:
402–404,
1978.
5.
PlattH.AthertonJ.G.DawsonF.L.M.DurrantD.S.:
Developments in contagious equine metritis. Isolation of the CEM organism from the clitoris of the mare.
Vet Rec102:
19,
1978.
6.
PlattH.AthertonJ.G.SimpsonD.J.:
The experimental infection of ponies with contagious equine metritis.
Equine Vet J10:
153–159,
1978.
7.
PowellD.G.:
Contagious equine metritis.
Equine Vet J10:
1–4,
1978.
8.
PowellD.G.DavidJ.S.E.FrankC.J.:
Contagious equine metritis: the present situation reviewed and a revised code of practice for its control.
Vet Rec103:
399–402,
1978.
9.
RickettsS.W.RossdaleP.D.SamuelC.A.:
Endometrial biopsy studies of mares with contagious equine metritis 1977.
Equine Vet J10:
160–166,
1978.
10.
RickettsS.W.RossdaleP.D.Wingfield-DigbyN.J.FalkM.M.HopesR.HuntM.D.N.PeaceC.K.:
Genital infection in mares.
Vet Rec101:
65,
1977.
11.
SahuS.P.PiersonR.E.DardiriA.H.:
Contagious equine metritis: effect of intrauterine inoculation of contagious equine metritis agent in pony mares.
Am J Vet Res41:
5–9,
1980.
12.
SwerczekT.W.:
CEM in horses: assuring diagnostic precision.
J Am Vet Med Assoc176:
406,
1980.
13.
TaylorC.E.D.RosenthalR.O.BrownD.F.J.LapageS.P.HillL.R.LegrosR.M.:
The causative organism of contagious equine metritis 1977: proposal for a new species to be known as Haemophilus equigenitalis.
Equine Vet J10:
136–144,
1978.
14.
TimoneyP.J.McArdleJ.F.O'ReillyP.J.WardJ.:
Infection patterns in pony mares challenged with the agent of contagious equine metritis 1977.
Equine Vet J10:
148–152,
1978.
15.
VandeplasscmeM.HenryM.:
Salpingitis in the mare.
Proc 23rd Annual Convention of the Amer Assoc of Equine Practitioners,
pp. 123–131,
1977.