The Impact of Warming Acupuncture–Moxibustion Combined with Xingnaojing Injection on Serum NSE,SOD,T Lymphocytes,and Prognosis in Severe Craniocerebral Trauma Patients
Restricted accessResearch articleFirst published online 2026
The Impact of Warming Acupuncture–Moxibustion Combined with Xingnaojing Injection on Serum NSE,SOD,T Lymphocytes,and Prognosis in Severe Craniocerebral Trauma Patients
The study aimed to assess the impact of combining warming acupuncture–moxibustion with Xingnaojing injection on serum levels of neuron-specific enolase (NSE), superoxide dismutase (SOD), T lymphocytes, and prognosis in severe head trauma patients. From January 2021 to February 2023, 98 severe craniocerebral trauma patients were randomly allocated into a control group and a treatment group, each comprising 49 cases. Both groups received conventional therapy. The control group was administered Xingnaojing injection, while the treatment group underwent warming acupuncture–moxibustion in addition to the control treatment. Changes in serum NSE, SOD levels, and T lymphocyte percentages pre- and posttreatments were analyzed between the groups. Additionally, neurological function scores and total response rates after treatment were compared. After treatment, there was a significant decrease in NSE levels, a noteworthy increase in SOD levels, and a substantial elevation in CD3+ and CD4+ T lymphocytes. Conversely, CD8+ T lymphocytes decreased significantly. The CD4+/CD8+ ratio showed a marked increase, and Glasgow coma scale (GCS) scores improved notably in both groups. The treatment group exhibited superior clinical efficacy compared to the control group, with statistically significant differences (p < 0.05). Combining warming acupuncture–moxibustion with Xingnaojing injection significantly alleviates oxidative stress and enhances immune function in severe craniocerebral trauma patients compared to using Xingnaojing injection alone. This combined treatment shows promising potential for better prognosis and clinical efficacy, warranting its consideration for wider clinical application.
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