Chemioterapia sistemica MVEC: 5 anni di esperienza: MVEC systemic chemotherapy: 5 years’ experience

The Authors describe their experience in treating 81 patients, suffering from urothelial cell carcinoma, with neo-adjuvant, adjuvant or final MVEC chemotherapy according to stage and localisation. The prospective results would seem to indicate conservative surgery and adjuvant chemotherapy for pT3N0M0G1-2 bladder tumours, prognostic improvement, at least with regard to disease-free period, in pT3N0M0 cancer, the possibility of downstaging in T4N + M + cancer and more clinical remissions in transitional cell carcinoma in the upper urinary tract. Furthermore, the therapy proved to be relatively easy for the “non-oncologist” urologists. Side effects are mentioned.