Benign prostatic hyperplasia with PSA > 10.0 ng/ml: Correlations between PSA density and pathological findings of the surgical specimen after open prostatectomy

— Thirty patients with benign prostatic hyperplasia and PSA levels > 10.0 ng/ml were submitted to open prostatectomy after a precise evaluation with transrectal ultrasound and prostatic biopsies. In the surgical specimen 7 prostatic carcinoma (23%) were found incidentally. In the remaining 23 patients the presence of active histological prostatitis was correlated with the PSA and PSA density values but was not directly due to an asymptomatic urinary infection or indwelling catheter. PIN and other pathological findings were not found to be correlated with PSA values.