Intravesical iontophoresis. Preliminary experience in 26 patients affected by superficial bladder tumours

– Intravesical iontophoresis should permit higher intratumoral concentrations of a drug administered intravesically for the treatment of superficial bladder tumours. Iontophoresis was performed with mitomycin C (30 mg in 60 ml) for 20 minutes using a pulsating electric current of 20 mA. Ten patients, with a papillary marker lesion left after TUR, were treated for ablative purposes. Sixteen other patients were submitted to intravesical prophylaxis after complete TUR. Toxicity was purely local. A complete response was obtained in 6 of the 10 patients with a marker lesion.