Clinician's Corner: Chatbots for Psychotherapy

McBain RK Bozick R Diliberti M , et al. Use of generative AI for mental health advice among US adolescents and young adults. JAMA Netw Open. 2025;8(11):e2542281.

Patten SB Williams JV Lavorato DH Wang JL McDonald K Bulloch AG . Major depression in Canada: What has changed over the past 10 years? Can J Psychiatry. 2016;61(2):80–85.

Frances A. Warning: AI chatbots will soon dominate psychotherapy. Br J Psychiatry. 2026;228(5):474–478.

Heinz MV Mackin DM Trudeau BM , et al. Randomized trial of a generative AI chatbot for mental health treatment. NEJM AI. 2025;2(4):AIoa2400802.

Siddals S Torous J Coxon A . “It happened to be the perfect thing”: Experiences of generative AI chatbots for mental health. NPJ Ment Health Res. 2024;3:48.

American Psychiatric Association. The basics of augmented intelligence: Some factors psychiatrists need to know now. New York, New York, USA: American Psychiatric Association; 2023, Accessed December 21, 2025. https://www.psychiatry.org/news-room/apa-blogs/the-basics-of-augmented-intelligence.

Reiley L. What my daughter told ChatGPT before she took her life. The New York Times 2025 Aug 18; Sect. SR:8 [cited 2026 Mar 29]. Available from https://www.nytimes.com/2025/08/18/opinion/chat-gpt-mental-health-suicide.html

Clark A . The ability of AI therapy bots to set limits with distressed adolescents: Simulation-based comparison study. JMIR Ment Health. 2025;12:e78414.

Lawrence H Schneider R Rubin S Matarić M McDuff D Jones Bell M . The opportunities and risks of large language models in mental health. JMIR Ment Health. 2024;11:e59479.