6-Mercaptopurine-Induced Muscular Lesions in Rats: Gross and Light Microscopic Pathology

Abstract

Keywords

6-Mercaptopurine muscular lesions pathology.

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References

Alleva, F.R. , Balazs, T. , Haberman, B.H. , Weinberger, M.A. and Slaughter, L.J. (1980). Muscular degeneration in rats after postnatal treatment with 6-mercaptopurine. Nineteenth Annual Meeting of Society of Toxicology, Washington, DC, April 9-13, p. A67 (Abstract).

Alleva, F.R. , Haberman, B.H. , Slaughter, L.J. and Balazs, T. (1981). Muscle degeneration in rats after postnatal treatment with 7-mercaptopurine. Drug Chem. Toxicol. 4:133-146.

Alleva, F.R. , Slaughter, L.J. , Abraham, A.A. , Balazs, T. (1984). Further studies on 6-mercaptopurine-induced muscle atrophy in rats, mice and hamsters treated as neonates. Pediatr. Pharmacol. 4:39-48.

Berg, B. (1956). Muscular dystrophy in aging rats. J. Gerontol. 11:134-139.

Cullen, M.J. and Brooke, M.H. (1973). Muscle Biopsy: A Modern Approach. W.B. Saunders Co., Ltd., London.

Hadlow, W.J. (1973). Myopathies of Animals. The Striated Muscle 12:364-409.

Montgomery, C.A. (1978). Muscle Diseases. In: Pathology of Laboratory Animals ( K. Benirschke , K., F.M. Garner and T.C. Jones , eds), Springer-Verlag, New York.

Slaughter, L.J. , Alleva, F.R. , Haberman, B.H. and Balazs, T. (1981). Muscular dystrophy-like syndrome in young adult Sprague-Dawley rats following neonatal treatment with 6-mercaptopurine. Toxicologic Pathology 9:38 (Abstract).