It of ten happens in science that clues to the nature of a problem under study come from
a completely different, seemingly unrelated, line of investigation. This may be the case
with MCS and Time-Dependent Sensitization (TDS), a phenomenon we discovered in rats in the
late 1970s and later named. TDS refers to the ability of mild stressors whether
pharmacological or environmental to induce physiological and behavioral effects which then
progress, i.e., get stronger, entirely as a function of the passage of time since stressor
presentation. This strengthening is revealed when the organism is later exposed to either
the original or another stressor. The characteristics of TDS bear a remarkable resemblance
to the features of MCS and that similarity is the subject of this manuscript.
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