Keratoconjunctivitis Sicca Due to Blepharoplasty Treated With Neurotoxin and Hyaluronic Acid Filler

Blepharoplasty is a common procedure for addressing eyelid laxity, thus enhancing functional and aesthetic eye concerns. This case report discusses a novel, minimally invasive treatment approach for severe dry eye resulting from lower eyelid blepharoplasty in a 57-year-old female. The patient experienced significant ocular discomfort 1-year post-surgery due to excessive skin removal, leading to ectropion and keratoconjunctivitis sicca (KCS) unresponsive to traditional therapies. Despite multiple attempts with conventional treatments, symptom relief remained minimal and significantly impacting the patient’s quality of life. A combined intervention using 28 units of prabotulinumtoxinA-xvfs and one syringe of hyaluronic acid filler alleviated symptoms by elevating the lower eyelid and restoring comfort. The treatment underscores the potential of combining neurotoxin and dermal filler as an alternative to surgical correction for post-blepharoplasty complications. In addition, this report highlights the importance of further research to determine specific treatment dosages and protocols when managing complex cases of eyelid retraction and dry eye syndrome.