Cinematic Rendering in Pancreatic Imaging: Tackling the CT Patterns of Serous Cystadenoma

Serous cystadenoma (SCA) is the most common benign cystic lesion of the pancreas, often an incidental finding on CT scans. Despite their characteristic features such as microcystic or honeycomb appearance, central scar, or lobulated margins, SCAs can display a range of morphologies, complicating their diagnosis and leading to potential confusion with premalignant or malignant lesions. Cinematic rendering (CR), a recent three-dimensional technique, producing striking lifelike images and enhancing visualization of subtle internal structures compared to conventional imaging. In this review, we demonstrate how CR improves the depiction of microcystic, honeycomb, macrocystic, and solid SCA patterns, as well as atypical features that can mislead radiologists. To the best of our knowledge, this is the first review to highlight CR’s ability to define the full spectrum of SCA appearances on CT. Case examples illustrate how CR accentuates tissue textures, clarifies spatial and vascular relationships, and highlights details such as septations and calcification. By refining assessment of internal and external lesion characteristics, CR has the potential to augment standard CT and facilitate accurate differentiation from other pancreatic lesions, reducing unnecessary interventions.