Review : Oligomeric Drug Carriers

Ringsdorf, H. "Structure and Properties of Pharmacologically Active Polymers," J. Polym. Sc. Symposia, 51:135 (1975).

Ringsdorf, H. "Synthetic Polymeric Drugs," Mid. Macro-Molecular Monogr. (Polym. Delivery Systems), 5:197 (1978).

Ferruti, P. "Macromolecular Drugs Acting as Precursors of Non-Macromolecular Active Substances. Preliminary Considerations," Pharmacol. Res. Commun. , 7:1 (1975).

Ferruti, P. , "Macromolecular Drugs," Il Farmaco, Ed. Sci., 3:220 ( 1977).

Batz, H.G. "Polymeric Drugs," Adv. in Polymer Sci., 23:25 ( 1977).

Pitha, J. "Polymer-Cell Surface Interactions and Drug Targeting," in Targeted Drugs. E. Goldberg , ed. New York:John Wiley and Sons, Chapter 6, p. 113.

Drobnik, J. and F. Rypacek. "Soluble Synthetic Polymers in Biological Systems," Advanc. Polym. Sci., 57:1 (1984).

Duncan, R. and J. Kopaček . "Soluble Synthetic Polymers as Potential Drug Carriers;" Advanc. Polym. Sci., 57:53 (1984).

Ferruti, P. "New Polymeric and Oligomeric Matrices as Drug Carriers," CRC Crytical Reviews in Therapeutical Drug Carriers Systems, 2(2):175 (1986).

Flory, J.P. "Principles of Polymer Chemistry," Ithaca Cornell University Prep (1956).

Ferruti, P. , A. Bettelli and A. Ferè. "High Polymers of Acrylic and Methacrylic Esters of N-Hydroxysuccinimide as Polyacrylamides and Polymethacrylamides Precursors," Polymer, 13:462 (1972).

Cecchi, R. , L. Rusconi , M.C. Tanzi , F. Danusso and P. Ferruti. "Synthesis and Pharmacological Evaluation of Poly(Oxyethylene) Derivatives of 4-Isobuthylphenyl-2-Propionic Acid (Ibuprofen," J. Med. Chem., 24:622 (1981).

Schaefer, H. , A. Zesch and G. Stüttgen in Skin Permeability. Berlin: Springer-Verlag, p. 625 onwards (1982).

Bauduin, G. , D. Bondon , Y. Pietrasanta , B. Pucci and F. Vial-Rèveillon. "Recherche de Télomères a Activitè Pharmacologique Potentielle. I. Etude de Télomères Comme Support de Médicaments ;" Eur. J. Med. Chem., Chim. Ter., 14:119 (1979).

Baudin, G. , S. Casadio , Y. Pietrasanta and B. Pucci. "Preparation and Pharmacological Activity of Biocompatible Medicine-Carrier Oligomers," Chim. and Ind. ( Milan), 62:421 (1980).

Bauduin, G. , D. Bondon , J. Martel , Y. Pietrasanta and B. Pucci. "Study on Télomers with Potential Pharmacological Activity. 2. Télomers of Acrylic Acid and Grafting of Hydroxylated Compounds," Makromol. Chem., 182:773 (1981).

Bauduin, G. , J.M. Bessière , D. Bondon , J. Martel and Y. Pietrasanta. "Recherche de Télomeres à Activite Pharmacologique Potentielle, 4. Reactions sur les Télomères de L'alcool Vinylique ," Makromol. Chem., 183:3397 (1981).

Bauduin, G. , J.M. Bessière , D. Bondon , J. Martel and Y Pietrasanta. "Recherche de Télomères è Activitè Pharmacologique Potentielle. 5. Reactions sur les Télomères de l'Acide Acrylique," Makromol. Chem., 183:3491 (1982).

Pinazzi, C. , A. Menil , J.C. Rabadeaux and A. Pleurdeau. "Polyisoprene and Polybutadiene Derivatives of Potential Biomedical Interest," J. Polym. Sci., Polym. Symp., 52:1 ( 1975).

Pinazzi, C. , J.C. Rabadeaux and A. Pleurdeau. "Polymers with Potential Pharmaceutical Properties: Fixation of Histamine on the Macromolecular Chain of Polyisoprene", J. Polym. Sc. (C), 15:1319 (1977).

Pinazzi, C. , A. Menil , J.C. Rabadeux and A. Pleurdeau (1974). "Polyisoprene and Polybutadiene Derivatives of Testosterone;" J. Polym. Sci., Polym. Letters, 12:447 (1974).

Pinazzi, C. , A. Menil and A. Pleurdeau. "Polymères à Proprietès Pharmaceutiques Potentielles. 1-Polyalkadienes à Extremitàs Fonctionelles," Bull. Soc. Chim. France, 3:667 (1975).

Pinazzi, C. , J.C. Rabadeux , A. Pleurdeau. "Polymerisation de Monomères à Structure Biologique;" Eur. Polym. J., 14:205 (1978).

Dal Pozzo, A. , M. Acquasaliente , G. Donzelli , F. Delor and P. Ferruti. "Synthesis and Antimicrobial Properties of New Aroylacrylic Esters of Polyethyleneglycols; " Il Farmaco, Ed. Sci., 41:622 (1986).

Dal Pozzo, A. , M. Acquasaliente , M. Buraschi and B.M. Anderson. "Synthesis of 4-oxo-4(3-phyridyl-2-butenoic Acids and Esters, a New Class of Nicotinoylacrylic Derivatives, Using the Methylsulphinyl Activating and Leaving Group," Synthesis, 926 (1984).

Dal Pozzo, A. , G. Donzelli and P. Ferruti. "New Functional Derivatives of Polyethyleneglycols: Bromoacetates and Betain Esters Therefrom ," Journ. Bioact. Compat. Polym. (1986).

Ferruti, P. , A.S. Angeloni , F. Andreani and P. Ferruti. "Nuovi Derivati Arildiidropiridinici Come Calcio Antagonisti ," Ital. Pat. Application N. 3339 A/85 (Feb. 19, 1985).

Ferruti, P. , M.C. Tanzi , L. Rusconi and R. Cecchi. "Succinic and Glutaric Half-Esters of Poly(ethylene glycol)s and their Benzotriazole and Imidazole Derivatives as Oligomeric Drug-Binding Matrices," Makromol. Chem., 182:2183 (1981).

Rusconi, L. , M.C. Tanzi , C. Zambelli and P. Ferruti. "Activated Derivatives of Succinic and Glutaric Half-Esters of Poly(propylene glycols), and their Exchange Reactions with Hydroxy- and Amino-Compounds," Polymer , 23:1689 (1982).

Buckmann, A.F. , M. Morr and G. Johansson. "Functionalization of Polyethyleneglycol and Monomethoxy—Polyethyleneglycol;' Makrom. Chem., 182:1379 (1981).

Harris, J.M. and J. Milton. "Laboratory Synthesis of Polyethyleneglycols Derivatives," J Macrom. Sci., Rev. Macromol. Chem. Phys., C25(3):325 and references therein (1985).

Tondelli, L. , M. Laus and A.S. Angeloni. "Polyethyleneglycol Imidazoyl Formates as Oligomeric Drug-Binding Matrices ," J. Controlled Release , 1:251 (1985).

Beuchamp, C.O. , S.L. Gonias , D.P. Menapace and S.V. Pizzo. "A New Procedure for the Synthesis of Polyethyleneglycol-Protein Adducts, Effect on Function, Receptor Recognition, and Clearance of Superoxide Dismutase, Lactoferrin, and 2-Macroglobulin," Anal. Biochem. , 131:25 (1983).

Zalipsky, S. , C. Gilon and A. Zilkha. "Attachment of Drugs to Polyethyleneglycols ," Eur. Polymer J., 19:1177 (1983).

Pitha, J. , R. Kociolek and M.G. Caron. "Detergents Linked to Polysaccharides : Preparation and Effects on Membranes and Cells," Europ. J. Biochem., 94:11 ( 1979).

Das, S.K. , S.R. Chatterjee and S.R. Palit. "Chain Tranfer-V Acrylonitrile," Proc. Roy. Soc. (London), A227:252 (1955).

Walling, C. "The Use of S35 in the Measurement of Transfer Constants," J. Am. Chem. Soc., 70:2561 (1948).

Ghedini, N. , P. Ferruti , V Andrisano, M.R. Cesaroni and G. Scapini. "Oligomeric Derivatives of 3 7β-dihydroxy-5β-cholan-24-oic Acid (Ursodeoxycholic acid," Synthetic Comm., 13:701 (1983).

Ferruti, P. , A.S. Angeloni , G. Scapini and M.C. Tanzi. "New Oligomers and Polymers as Drug Carriers," in Recent Advances in Drug Delivery Systems. J. M. Anderson and S. W. Kim , eds. New York:Plenum Press, p. 63 (1984).

Weiner, B.Z. and A. Zilkha. "Polyethyleneglycols Derivatives of Procaine ," J. Med. Chem., 16:573 (1973).

Weiner, B.Z. , A. Zilkha , G. Porath and Y. Grunfeld. "Atropine Attached to Polyethylene Glycols ," Eur. J. Med. Chem., Chim. Ter. , 11:525 (1976).

Weiner, B.Z. , A. Havron and A. Zilkha. "Salicylates Attached to Polymers ," Isr. J. Chem., 12:863 (1974).

Narcisse, G. , J. Choay , P. Choay and C. Pinazzi. "Étude Pharmacodynamique d'un Derive Polimérique de la Testostérone," Thérapie, 34:95 ( 1979).

Ghedini, N. , V. Andrisano , V. Zecchi , A. Tartarini , G. Scapini and P. Ferruti. "Synthesis and Partition Profiles of Nicotinoyl Derivatives of Polyethyleneglycols and Polypropyleneglycols ," J. Controlled Release, 3:185 (1986).