We present a case of ecthyma gangrenosum caused by Stenotrophomonas maltophilia in an immunocompromised patient with aplastic anemia and on antithymocyte globulin therapy, cyclosporine, and methylprednisolone treatment. We also conducted a brief literature review on ecthyma gangrenosum caused by Stenotrophomonas maltophilia to determine optimal treatment and expected duration of therapy for infection management. This report highlights the key clinical challenges in determining optimal treatment duration for this uncommon condition taking into account underlying host factors.
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