Practical Issues in Handling Biotechnology Products

The unique nature of biotechnology products requires specific additional education and training for pharmacists. To understand how these products were developed and their mechanism of action, expanded knowledge in molecular biology, immunology, genetics, and the techniques of biotechnology is essential. Since these products are often used for disease states that were not previously treated with drug therapy, a basic understanding of the pathophysiology of the disease being treated is essential. Many biotechnology products are administered parenterally, and pharmacists must be familiar with these methods of administration to provide proper equipment, guidance, and counseling for patients. Stability and compatibility issues frequently arise with biotechnology products as many require refrigeration, special diluents, and are susceptible to compatibility problems. Because these products are often used in chronic disease settings and because patients may be expected to self-administer using a parenteral route, drug therapy monitoring and patient education needs are often substantial. The patient education role, in particular, may be the most important responsibility for pharmacists providing care to patients undergoing treatment with biotechnology products.