Hydrolytic Stability of Some Thermoplastic Poly(Ether-Urethane-Urea)s

Abstract

Two thermoplastic poly(ether-urethane-urea)s were synthesized from isophorone diisocyanate, hexamethylene diamine, and polyethylene glycol as macrodiol. The molecular weight of the macrodiol was 2000 g mol⁻¹. The polymers have been characterized by means of transmission electron microscopy, ¹H-NMR, infrared spectroscopy, and other techniques. The hydrolytic stability of these materials was investigated under in vitro condition using Ringer's solution and phosphate-buffered saline. The stability of these series was compared with a poly(ether-urethane) prepared from isophorone diisocyanate, polyethylene glycol and 1,4-butanediol. The in vitro study revealed possible use of poly(ether-urethane-urea)s for long-term biomedical applications.

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