Azopolysiloxanes Modified with Nucleobases: 1. Thermal Characterization of some Nanostructurable Materials with Potential Application in Biology

Abstract

New azopolysiloxanes modified with nucleobases with potential application in biology were synthesized and their thermal stability was evaluated. These types of materials can present two possible applications: obtaining of films with nanostructured surface that may be used in cell directional development control and in biomolecular binding and nanohandling. Both applications involve, however, material interaction with laser beams, which require a series of precautions with regard to polymer thermal stability. We considered it essential to perform very thorough thermal stability studies that would provide accurate information concerning the lowest temperature at which thermal degradation occurred. Some correlations between structure—thermal stability were derived.

Keywords

Azopolysiloxanes nucleobases thermal stability

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References

Sivakova, S. and Rowan, S.J. (2005). Nucleobases as Supramolecular Motifs, Chem. Soc. Rev., 34: 9-21.

Ilhan, F. , Gray, M. and Rotello, V.M. (2001). Reversible Side Chain Modification through Noncovalent Interactions. Plug and Play Polymers, Macromolecules, 34: 2597-2601.

Lutz, J.F. , Thunemann, A.F. and Nehring, R. (2005). Preparation by Controlled Radical Polymerization and Self-Assembly via Base-Recognition of Synthetic Polymers Bearing Complementary Nucleic Acids, J. Polym. Sci. Polym. Chem., 43: 4805-4818.

Yoshinari, M. , Matsuzaka, K. , Inoue , T. , Oda , Y. and Shimono, M. (2003). Effects of Multigrooved Surfaces on Fibroblast Behavior, J. Biomed. Mater. Res. A , 65A: 359-368.

Lu, X. and Leng, Y.J. (2003). Quantitative Analysis of Osteoblast Behavior on Microgrooved Hydroxyapatite and Titanium Substrata, Biomed. Mater. Res. A, 66: 677-687.

Snyder, J.D. and Desai, T.A. (2001). Fabrication of Multiple Microscale Features on Polymer Surfaces for Applications in Tissue Engineering Biomed. Microdevices, 3: 293-300.

Hurduc, N. , Enea, R. , Scutaru , D. , Sacarescu, L. , Donose, B.C. and Nguyen, A.V. (2007). Nucleobases Modified Azo-Polysiloxanes, Materials with Potential Application in Biomolecules Nanomanipulation , J. Polym. Sci. Polym. Chem , 45: 4240-4248.

Rochon, P. , Batalla, E. and Natansohn, A. (1995). Optically Induced Surface Gratings on Azoaromatic Polymer Films, Appl. Phys. Lett., 66: 136-138.

Kim, W.H. , Bihari, B. , Moody , R. , Kodali, N.B. , Kumar, J. and Tripathy, S.K. (1995). Self-Assembled Spin-Coated and Bulk Films of a Novel Poly(diacetylene) as Second-Order Nonlinear Optical Polymers, Macromolecules, 28: 642-647.

10.

Karageorgiev, P. , Neher, D. , Schulz , B. , Stiller, B. , Pietsch, U. , Giersig, M. and Brehmer, L. (2005). From Anisotropic Photo-Fluidity Towards Nanomanipulation in the Optical Near-Field, Nat. Mater., 4: 699-703.

11.

Kazmierski, K. , Hurduc, N. , Sauvet , G. and Chojnowski, J. (2004). Polysiloxanes with Chlorobenzyl Groups as Precursors of New Organic-Silicone Materials, J. Polym. Sci. Polym. Chem., 42: 1682-1692.

12.

Zhou, W. , Yang, Y. , Guo, X. and Lu, J. , (2006). Thermal Degradation Behaviors of some Branched and Linear Polysiloxanes, Polym. Degrad. Stabil., 91: 1471-1475.

13.

Jovanovic, J.D. , Govedarica, M.N. , Dvornic , P.R. and Popovic, I.G. (1998). The Thermogravimetric Analysis of Some Polysiloxanes, Polym. Degrad. Stabil., 61: 87-93.

14.

Zulfigar, S. and Ahmad, S. (2001). Thermal Degradation of Blends of PVAC with Polysiloxane: II, Polym. Degrad. Stabil . 71: 299-304.

15.

Keniry, M.A. , Owen, E. and Shafer, R. (1997). The Contribution of Thymine-Thymine Interactions to the Stability of Folded Dimeric Quadruplexes, Nucleic Acids Res., 25: 4389-4392.

16.

Creanga, A. , Hurduc, N. , Pokol, G. , Novák, C. , Alazaroaie, S. and Hurduc, N. (2002). Degradation Mechanism Using TG-MS Technique of some Aromatic Polyethers. Containing Flexible Spacers, J. Thermal Anal. Cal., 70: 877-887.

17.

Hurduc, N. , Damian, C. , Tarus, A. , Toader, V. and Hurduc, N. (2005). Thermal Behavior of some Aromatic Copolyethers Containing a Propylenic Spacer, Cent. Eur. J. Chem., 3: 53-62.