The understanding of basic surface properties and the relationships between temperature and the configuration of the polymer surface are the key to further understand the first interaction mechanism of the polymer with the body. To this end, some poly(carbonate tetramethylene ether)urethane (PCEU), poly(carbonate siloxane tetramethylene ether)urethane (PCSiEU), and their 1:1 gravimetric mixture (PCEU/PCSiEU) membranes were prepared. In order to establish the relationships between temperature and the chemical structure of polymer surface, the polyurethane (PU) membranes were analyzed by attenuated total reflectance–Fourier transform infrared spectroscopy. The temperature has a significant influence on these PU surface structures. Surface characteristics such as wettability and surface free energy were also analyzed since the interaction between biomaterials and blood occurs at their interface. The preliminary cytotoxicity screening showed no cytotoxicity of these PU membranes. The PU samples do not accelerate the clot formation mechanisms under the tested conditions. The results suggest that these PU membranes are promising materials for the preparation of cardiovascular scaffolds.
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