Recurrent Annular Erythema Anti-SSA/Ro and Anti-SSB/La Antibodies Localized on Palms and Fingers an Elderly Man

Abstract

A 69-year-old Japanese man with recurrent annular erythema localized on palms and flexor surface of fingers with anti-SSA/Ro and anti-SSB/La antibodies, is reported. The present case indicates that even in an elderly man with atypical localization, annular erythema with autoimmunity may be considered and serological analysis should be performed. Systematic studies will be required to understand the relationship between 'recurrent annular erythema associated with anti-SSB/La antibodies' in Japanese, subacute cutaneous lupus erythematosus (SCLE) and 'annular erythema associated with Sjogren's syndrome'.

Keywords

Subacute cutaneous lupus erythematosus Anti-SSB/La antibodies Anti-SSA/Ro antibodies Annular erythema Sjogren's syndrome

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References

McCauliffe DP , Sontheimer RD Subacute cutaneous lupus erythematosus. In: Dubois' Lupus Erythematosus , Wallace DJ , Hahn BH (eds). Philadelphia , Lea & Febiger, 1993, 302-9.

Nishikawa T. , Hayakawa K. , Takahashi S. , Kawakubo H. , Yamagata H. , Akizuki M. Recurrent erythema associated with immunological abnormalities: anti-SSB recurrent erythema. Jpn J Dermatol 1988; 98: 825-34 (in Japanese).

Hoshino Y. , Hashimoto T. , Mimori T. , Akizuki M. , Nishikawa T. Recurrent annular erythema associated with anti-SSB/La antibodies: analysis of the disease specific epitope. Br J Dermatol 1992; 127: 608-13.

Nishikawa T. , Provost TT Differences in clinical, serological and immunogenetic features of white versus Oriental anti-SSA/Ro-positive patients . J Am Acad Dermatol 1991; 25: 563-4.

Ruzicka T. , Faes J. , Bergner T. , Peter RU , Braun-Falco O. Annular erythema associated with Sjogren's syndrome: a variant of systemic lupus erythematosus. J Am Acad Dermatol 1991 ; 25: 557-60.

Teramoto N. , Katayama I. , Arai H. et al. Annular erythema: a possible association with primary Sjogen's syndrome. J Am Acad Dermatol 1989; 20: 596-601.

Alexander EL , Provost TT

Cutaneous manifestations of primary Sjogren's syndrome: a reflection of vasculitis and association with anti-Ro(SSA) antibodies. J. Invest

Dermatol 1983; 80: 386-91.

Inagaki Y. , Jinno Y Hamasaki Y, Ueki H. Higher incidences of anti-SSA/Ro and anti-SSB/La autoantibodies in Japanese patients with autoimmune disorders: studies of antigens and antibodies using the immunoblotting method. Arch Dermatol Res 1989; 281: 89-94.

St. Clair EW Anti-La antibodies. Rheum Dis Clin North Am 1992; 18: 359-76.

10.

Satoh M. , Akizuki M. , Kuwana M. et al. Genetic and immunological differences between Japanese patients with diffuse scleroderma and limited scleroderma. J Rheumatol 1994; 21: 111-14.