First episode mania following cessation of varenicline (Champix)

Abstract

Objectives:

To describe a case of first episode mania and in which varenicline (Champix) or its withdrawal appears to have been the precipitating factor.

Methods:

The clinical presentation and progress are detailed and the relevant literature in relation to varenicline is provided.

Results:

The case report adds to the literature indicating that varenicline may induce a range of mood states, albeit with reported incidents of mania being rare.

Conclusions:

In reviewing causes of mood states, including mania, seeking information on any exposure to varenicline would appear to be relevant.

Keywords

varenicline mania psychosis bipolar disorder

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