Neonatal teratoma, a common congenital malformation, rarely occurs in the head and neck region, especially not within the oral cavity. This report presents a case of neonatal giant teratoma in the oral cavity and oropharynx along with cleft palate, which caused postnatal airway obstruction and respiratory distress and required postnatal resection in a female newborn. After the delivery and routine neonatal examination, the anesthesiologist conducted orotracheal intubation to establish the airway, and tumor resection was immediately done under local anesthesia. The optimal treatment of neonatal teratoma is exclusive emergent surgery. Immediate postnatal resection is necessary to prevent airway obstruction.
AndersonPJDavidDJ. Teratomas of the head and neck region. J Craniomaxillofac Surg. 2003;31(6):369-377.
2.
PangXKwonHJShiBLiC. A rare nasopharyngeal teratoma arising from the vomer. J Craniofac Surg. 2016;27(2):e165-e166.
3.
DakpeSDemeerBCordonnierCDevauchelleB. Emergency management of a congenital teratoma of the oral cavity at birth and three-year follow-up. Int J Oral Maxillofac Surg. 2014;43(4):433-436.
4.
HeJWangYZhuHQiuWHeY. Nasopharyngeal teratoma associated with cleft palate in newborn: report of 2 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(2):211-216.
5.
MakkiFMAl-MazrouKA. Nasopharyngeal teratoma associated with cleft palate in a newborn. Eur Arch Otorhinolaryngol. 2008;265(11):1413-1415.
6.
LudwigAKSutcliffeAGDiedrichKLudwigM. Post-neonatal health and development of children born after assisted reproduction: a systematic review of controlled studies. Eur J Obstet Gynecol Reprod Biol. 2006;127(1):3-25.
7.
SchieveLARasmussenSABuckGMSchendelDEReynoldsMEWrightVC. Are children born after assisted reproductive technology at increased risk for adverse health outcomes?Obstet Gynecol. 2004;103(6):1154-1163.
8.
SagotPBechouaSFerdynusCFacyAFlammXGouyonJBJimenezC.Similarly increased congenital anomaly rates after intrauterine insemination and IVF technologies: a retrospective cohort study. Hum Reprod. 2012;27(3):902-909.
9.
ReefhuisJHoneinMASchieveLACorreaAHobbsCARasmussenSA.Assisted reproductive technology and major structural birth defects in the United States. Hum Reprod. 2009;24(2):360-366.
10.
EricsonAKallenB. Congenital malformations in infants born after IVF: a population-based study. Hum Reprod. 2001;16(3):504-509.
11.
PasupathyMNarayananPVManiVAdenwallaHS. A case report of nasopharyngeal teratoma with a cleft palate and an inguinal hernia. J Plast Reconstr Aesthet Surg. 2011;64(11):1525-1527.
12.
BatsakisJGEl-NaggarAKLunaMA. Teratomas of the head and neck with emphasis on malignancy. Ann Otol Rhinol Laryngol. 1995;104(6):496-500.
13.
ParajuliRThapaSMaharjanS. Mature nasopharyngeal teratoma in a child. Case Rep Otolaryngol. 2015;2015:515474. https://doi.org/10.1155/2015/515474
14.
MaedaYSuenagaHSugiyamaMSaijoHHoshiKMoriYTakatoT.Clinical presentation of epignathus teratoma with cleft palate; and duplication of cranial base, tongue, mandible, and pituitary gland. J Craniofac Surg. 2013;24(4):1486-1491.
15.
HanHHKimJHSeoBFMoonSHOhDYRhieJW.Huge nasopharyngeal teratoma with a cleft palate and bifid tongue in a patient with Pierre Robin syndrome. J Craniofac Surg. 2014;25(6):e588-e590.
16.
VeyssiereAStreitLTraoreHBenateauH. Cleft palate caused by congenital teratoma. Paediatr Int Child Health. 2017;37(1):66-69.
17.
SkarsgardEDChitkaraUKraneEJRileyETHalamekLPDedoHH.The OOPS procedure (operation on placental support): in utero airway management of the fetus with prenatally diagnosed tracheal obstruction. J Pediatr Surg. 1996;31(6):826-828.
