Management of Drug Interactions in Patients with HIV

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Eron J.J. , Benoit S.L. , Jemsek J. , MacArthur R.D. , Santana J. , Quinn J.B. Treatment with lamuvidine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. N Engl J Med 1995; 333: 1662-9.

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Bailey D.G. . Food-drug interactions: emphasis on grapefruit juice effects. Can J Clin Pharmacol 1995; 2: 10-4.

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Lee B.L. , Tuber M.G. , Chambers H.R. , Gambertoglio J. , Delahunty T. . The effect of trimethoprim on the pharmacokinetics of zalcitabine in HIV-infected patients (abstract). Presented at the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA, September 17-20, 1995.

Pastore A. , Van Cleef G. , Risher E.J. , Gillum J.G. , LeBel M. , Polk R.E. . Dideoxycytidine pharmacokinetics and interaction with clarithromycin in patients seropositive for HIV (abstract). Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

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Morse G.D. , Fischl M.A. , Shelton M.J. , Cox S.R. , Driver M. , DeRemer M. Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection. Antimicrob Agents Chemother 1997; 41: 169-74.

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Ferry J. , Herman B. , Cox S. , Carlson G. , Carberry P. . Delavirdine (DLV) and indinavir (IDV): a pharmacokinetic (PK) drug–drug interaction study in healthy adult volunteers. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

Ferry J. , Schneck D. , Carlson G. , Carberry P. , Della-Coletta A. , Gulotti B. Evaluation of the pharmacokinetic (PK) interaction between ritonavir (R) and delavirdine (DLV) in healthy volunteers. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

Cox S. , Batts D. , Stewart F. , Buss N. , Brown A. , Chambers J. Evaluation of the pharmacokinetic (PK) interaction between saquinavir (SQV) and delavirdine (DLV) in healthy volunteers. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22–26, 1997.

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Gagnier P. , Myers M. , Lamson M. , Greguski R. , Love J. , Chodakewitz J. . Effect of nevirapine (NVP) on pharmacokinetics (PK) of indinavir (IDV) in HIV-1 patients. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

Lamson M. , Gagnier P. , Greguski R. , Myers M. , Leonard J. , Lauva I. Effect of nevirapine (NVP) on pharmacokinetics (PK) of ritonavir (RTV) in HIV-1 patients. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

Sahai J. , Cameron W. , Salgo M. , Stewart F. , Myers M. , Lamson M. Drug interaction study between saquinavir (SQV) and nevirapine (NVP). Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

Lee C.A. , Liang B.H. , Wu E.Y. , Grettenberger H.M. , Sandoval T.M. , Zhang K.E. Prediction of nelfinavir mesylate (VIRACEPT) clinical drug interactions based on in vitro human P450 metabolism studies. Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

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McCrea J. , Buss N. , Stone J. , Carides A. , Dru J. , Stewart F. Indinavir-saquinavir single dose pharmacokinetic study (abstract). Presented at the 4th National Conference on Retroviruses and Opportunistic Infections, Washington, DC, January 22-26, 1997.

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