Although more than 90% of pancreatic tumors represent primary tumors, specifically ductal adenocarcinomas, metastatic tumors are not infrequent at this site. Metastasis of salivary gland tumors to the pancreas is exceedingly rare, with only a few cases reported in the English-language medical literature. Here, we report a patient with metastatic adenoid cystic carcinoma to the pancreas, 24 months following the initial diagnosis, and review the available literature on secondary tumors located in the pancreas with an emphasis on tumors of salivary gland origin.
AdsayNVAndeaABasturkOKilincNNassarHChengJD. Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchows Arch. 2004;444(6):527‐535. doi:https://doi.org/10.1007/s00428-004-0987-3
2.
SpadacciniMBellocchiMCMangiavillanoB, et al.Secondary tumors of the pancreas: a multicenter analysis of clinicopathological and endosonographic features. J Clin Med. 2023;12(8):2829.
3.
MasettiMZaniniNMartuzziF, et al.Analysis of prognostic factors in metastatic tumors of the pancreas: a single-center experience and review of the literature. Pancreas. 2010;39(2):135‐143.
4.
NakamuraEShimizuMItohT, et al.Secondary tumors of the pancreas: clinicopathological study of 103 autopsy cases of Japanese patients. Pathol Int. 2001;51(9):686–690.
5.
GeigerJGarciaJPriceK. Acinic cell carcinoma of the salivary gland with metastatic spread to the pancreas. Case Rep Oncol. 2014;7(1):195‐198.
6.
FalkGAEl-HayekKMorris-StiffGTuthillRJWinansCG. Adenoid cystic carcinoma of the base of the tongue: late metastasis to the pancreas. Int J Surg Case Rep. 2011;2(1):1‐3.
7.
DavidDMasineniSGiorgadzeT. Fine-needle aspiration diagnosis of high-grade adenoid cystic carcinoma metastatic to the pancreas. Diagn Cytopathol. 2015;43(2):117‐120.
8.
GandhiAKRoySBiswasA, et al.Adenoid cystic carcinoma of head and neck: a single institutional analysis of 66 patients treated with multi-modality approach. Indian J Med Paediatr Oncol. 2015;36(3):166‐171.
9.
KoJJSieverJEHaoDSimpsonRLauHY. Adenoid cystic carcinoma of head and neck: clinical predictors of outcome from a Canadian centre. Curr Oncol. 2015;23(1):26‐33. doi:https://doi.org/10.3747/co.23.2898
10.
BradleyPJ. Adenoid cystic carcinoma evaluation and management: progress with optimism!Curr Opin Otolaryngol Head Neck Surg. 2017;25(2):147‐153.
11.
AtallahSMarcMSchernbergA,et al.Beyond surgical treatment in adenoid cystic carcinoma of the head and neck: a literature review. Cancer Manag Res. 2022;4(14):1879‐1890. doi:https://doi.org/10.2147/CMAR.S355663
