Isolated Renal Mucormycosis Simulating a Renal Neoplasm in a Patient With the Acquired Immunodeficiency Syndrome

We report the case of a terminally ill patient with the acquired immunodeficiency syndrome who presented with a tender enlarged renal mass that simulated a renal neoplasm. A needle biopsy of the kidney revealed ischemic necrosis, vascular destruc tion, and fungal forms consistent with infection by the Zygomycetes family. Subse quently, autopsy confirmed this diagnosis and established that the kidney was the sole site of this fungal infection. Since fungal infections of the kidney simulating a renal tumor have not previously been described in acquired immunodeficiency syndrome, this report expands the list of lesions produced by opportunistic infections arising in a setting of human immunodeficiency virus-induced immunosuppression. Int J Surg Pathol 2(2):163-168, 1994