TalaricoL., ChenG., PazdurR.. Enrollment of elderly patients in clinical trials of cancer drug registration: a 7-year experience by the US Food and Drug Administration.J Clin Oncol.2004; 22(22): 4626–4631.
2.
LutfullinA., KuhlmannJ., WensingG.. Adverse events in volunteer participating in phase I clinical studies: a single-center 5-year survey in 1,559 subjects.Intern J Clin Pharmacol Ther.2005; 43(5): 227–236.
3.
BorkowskiJ.M., DuerrM., DonehowerR.C.. Relation between age and clearance rate of nine investigational anticancer drugs from phase I pharmacokinetic data.Cancer Chemother Pharmacol.1994; 33(6): 493–496.
4.
van HeeckerenW.J., FuP., BarrP.M.. Safety and tolerability of phase I/II clinical trials among older and younger patients with acute myelogenous leukemia.J Geriatr Oncol.2011; 2(3): 215–221.
5.
ZafarS.F., HeilbrunL.K., VishnuP.. Participation and survival of geriatric patients in phase I clinical trials: the Karmanos Cancer Institute (KCI) experience.J Geriatr Oncol.2011; 2(1): 18–24.
6.
ExtermannM., BolerI., ReichR.R.. Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale in High age patients (CRASH) score.Cancer.2012; 118(13): 3377–3386.
7.
HurriaA., TogawaK., MohileS.T.. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.J Clin Oncol.2011; 29(25): 3457–3465.
8.
PopaM.A., WallaceK.J., BrunelloA.. Potential drug interactions and chemotoxicity in older patients with cancer receiving chemotherapy.J Geriatr Oncol.2014; 5(3): 307–314.
9.
BalducciL., Goetz-PartenD., SteinmanM.A.. Polypharmacy and the management of the older cancer patient.Ann Oncol.2013; (24 suppl 7): vii36–vii40.
10.
KellyC.M., PowerD.G., LichtmanS.M.. Targeted therapy in older patients with solid tumors.J Clin Oncol.2014; 32(24): 2635–2646.
11.
KorkolaJ., GrayJ.W.. Breast cancer genome–form and function.Curr Opin Genet D ev.2010; 20(1): 4–14.
12.
BalducciL.. Studying cancer treatment in the elderly patient population.Cancer Control.2014; 21(3): 215–220.
13.
VaradhanR., YaoW., MatteiniA.. Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults.J Gerontol A Biol Sci Med Sci.2014; 69(2): 165–173.
14.
QuS., WenW., ShuX.O.. Association of leukocyte telomere length and breast cancer risk: nested case-control findings from the Shanghai Women's Health study.Am J Epidemiol.2013; 177(7): 617–624.
15.
FalandryC., BonnefoyM., FreyerG.. Biology of cancer and aging: a complex association with cellular senescence.J Clin Oncol.2014; 32(24): 2604–2610.
DensonA.C., MahipalA.. Participation of the elderly population in clinical trials: barriers and solutions.Cancer Control.2014; 21(3): 209–214.
18.
GaddipatiH., FuP., DowlatiA.. Phase I clinical trials in patients ≥80.J Geriatr Oncol.2011; 2(2): 142–146.
19.
SchwandtA., HarrisP.J., HunsbergerS.. The role of age on dose-limiting toxicities in phase I dose-escalation trials.Clin Cancer Res.2014; 20(18): 4768–4775.
20.
NosratyL., JylhäM., RaittilaT.. Perceptions of the oldest old on successful aging, Vitality 90+ Study.J Aging Study.2015; 32: 50–58.